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Understanding Specifications: A Deep Dive into (S)-3-Amino-1-benzylpiperidine

For professionals in the pharmaceutical and fine chemical sectors, a thorough understanding of product specifications is fundamental. This is especially true for key intermediates like (S)-3-Amino-1-benzylpiperidine (CAS: 307532-02-1). Whether you are a research scientist developing new drug candidates or a quality control manager ensuring batch consistency, knowing the precise characteristics of this chiral amine is vital. This article provides an in-depth look at its specifications, helping you make informed purchasing decisions when you intend to buy this compound.

Key Chemical and Physical Properties

(S)-3-Amino-1-benzylpiperidine is characterized by its molecular formula C12H18N2 and a molecular weight of approximately 190.28 g/mol. However, it is commonly supplied as its dihydrochloride salt, with a molecular formula of C12H20Cl2N2 and a molecular weight of 263.21 g/mol. The melting point is a significant indicator of purity and stability, typically reported as 237°C with decomposition. Its stability is generally considered good at room temperature in closed containers, which is a crucial factor for storage and handling by research and development teams.

Purity and Analytical Data

The purity of (S)-3-Amino-1-benzylpiperidine is a critical specification, often reported as 95% minimum or higher for standard grades. Suppliers may provide a Certificate of Analysis (COA) detailing purity determined by methods such as HPLC or GC. For advanced applications, even higher purity levels might be required, which can often be achieved through custom synthesis. Familiarizing yourself with the typical analytical data, such as NMR spectra, provided by a supplier is essential for verifying the identity and quality of the material before you buy.

Handling, Storage, and Safety

Proper handling and storage are essential to maintain the integrity of (S)-3-Amino-1-benzylpiperidine. It should be stored in a cool, dry, and well-ventilated area, away from incompatible materials. Safety information, typically including hazard codes (e.g., Xi, T) and risk statements (e.g., 36/37/38-25), should be carefully reviewed. As a chemical intermediate, appropriate personal protective equipment (PPE) should always be used when handling it. Understanding these specifications ensures that you can safely and effectively integrate this compound into your research or manufacturing processes.

Choosing a Reliable Supplier

When you need to purchase (S)-3-Amino-1-benzylpiperidine, selecting a supplier that clearly communicates these specifications is paramount. Look for manufacturers and distributors who provide detailed product information, including purity, physical properties, and safety data. This transparency builds trust and ensures that you are receiving a product that meets your project's exacting demands.

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