For professionals engaged in chemical synthesis, particularly in the pharmaceutical and fine chemical sectors, a deep understanding of product specifications is fundamental. Trans-4-Hydroxycyclohexanecarboxylic Acid (CAS 3685-26-5) is a key intermediate, and its precise specifications directly impact the success of downstream applications. This article breaks down the critical parameters to consider when you look to buy this compound.

The primary specification for any chemical intermediate is its purity. Trans-4-Hydroxycyclohexanecarboxylic Acid is typically required at high purity levels, often 99% or more. This is achieved through meticulous synthesis and purification processes by the manufacturer. High purity ensures that the compound will react as expected, minimizing side reactions and the formation of unwanted byproducts, which is especially critical in pharmaceutical synthesis where even trace impurities can have significant consequences.

The chemical structure and stereochemistry are also paramount. The CAS number 3685-26-5 uniquely identifies Trans-4-Hydroxycyclohexanecarboxylic Acid, distinguishing it from its cis isomer or other related compounds. The 'trans' configuration, indicating that the hydroxyl and carboxylic acid groups are on opposite sides of the cyclohexane ring, is vital for its intended reactivity and the stereochemical outcome of subsequent reactions. Researchers and formulators need to ensure they are procuring the correct isomer.

Other important specifications include:

• Molecular Formula and Weight: C7H12O3 and 144.17 g/mol respectively. These are fundamental identifiers and are crucial for stoichiometric calculations in synthesis.
• Appearance: The compound is generally described as a white to off-white solid or powder. Visual inspection can be an initial indicator of gross contamination, though it doesn't replace rigorous analytical testing.
• Melting Point: While variable depending on purity and polymorphic form, a consistent melting point range is often provided by manufacturers, serving as a reference point for quality.
• Solubility: Understanding its solubility in common solvents (e.g., water, DMSO, organic solvents) is essential for designing reaction conditions and purification procedures.

When sourcing Trans-4-Hydroxycyclohexanecarboxylic Acid, it is crucial to engage with a reliable supplier that provides comprehensive documentation, including a detailed Certificate of Analysis (CoA) with each batch. This CoA should clearly outline the purity, assay results, and other relevant physical and chemical properties verified by the manufacturer.

For businesses looking to purchase this intermediate, particularly in bulk, understanding these specifications is a cornerstone of effective procurement. Competitive price is important, but it should never come at the expense of quality and compliance with essential specifications. Partnering with experienced China-based manufacturers can often provide an optimal balance of quality and cost-effectiveness.

In summary, a thorough understanding of the specifications for Trans-4-Hydroxycyclohexanecarboxylic Acid (CAS 3685-26-5) is non-negotiable for any professional involved in its use. From purity to stereochemistry and physical properties, each parameter plays a critical role in ensuring successful and reproducible chemical synthesis.