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11-Aminoundecanoic Acid (CAS 2432-99-7) is a bifunctional molecule that has garnered significant attention in the chemical and pharmaceutical industries due to its versatile applications. Understanding its synthesis, properties, and applications is key for researchers and procurement specialists seeking high-quality chemical intermediates. This compound, characterized by its amine and carboxylic acid functionalities separated by an eleven-carbon chain, serves as a foundational element in numerous complex chemical syntheses.
The production of 11-Aminoundecanoic Acid typically involves a multi-step synthesis. A common route begins with castor oil, a readily available natural resource. Through processes like transesterification, pyrolysis, and subsequent chemical transformations including hydrolysis and hydrobromination, followed by amination or a bromine exchange method, the desired product is obtained. Manufacturers often strive for efficient processes to ensure a consistent supply of high-purity 11-Aminoundecanoic Acid, commonly specified at 97% minimum purity.
The applications of 11-Aminoundecanoic Acid are broad and impactful. In pharmaceutical research, it is extensively used as a PROTAC linker, facilitating the development of targeted protein degradation therapies. Its structure is ideal for connecting the target-binding molecule with the E3 ligase recruiter. Additionally, it plays a role in synthesizing analogues for cancer therapy research, specifically those targeting apoptosis in cancer cells. Its utility also extends to creating peptide-based matrix metalloproteinase inhibitors, contributing to treatments for various diseases.
For professionals looking to purchase 11-Aminoundecanoic Acid, identifying reliable suppliers and manufacturers is essential. Many seek out '11-Aminoundecanoic Acid manufacturers in China' due to the country's robust chemical production capabilities and competitive pricing. When evaluating suppliers, factors such as product purity, batch-to-batch consistency, and timely delivery are critical considerations.
The compound's physical appearance is typically a white solid or powder, with a melting point around 188-191 °C. Its molecular formula is C11H23NO2, and its molecular weight is 201.306 g/mol. These specifications are vital for chemists to accurately incorporate it into their synthesis schemes.
In summary, 11-Aminoundecanoic Acid is a valuable and multifaceted intermediate. Its growing importance in drug discovery, particularly in areas like targeted protein degradation and cancer therapeutics, highlights the need for dependable sources. For those in the pharmaceutical and chemical industries, securing high-quality 11-Aminoundecanoic Acid from reputable manufacturers is a strategic step towards successful innovation.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
