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Understanding the Synthesis and Properties of 4-Fluoro-2-methoxyaniline

4-Fluoro-2-methoxyaniline (CAS 450-91-9) is a complex organic compound with significant utility across pharmaceutical and fine chemical industries. Understanding its synthesis and inherent properties is crucial for any professional looking to buy or utilize this intermediate effectively. At NINGBO INNO PHARMCHEM CO.,LTD., we pride ourselves on being a leading manufacturer and supplier in China, ensuring that our clients receive a product of exceptional quality and consistency. This article aims to provide insights into how this vital compound is made and its defining characteristics.

The primary synthesis route for 4-Fluoro-2-methoxyaniline commonly involves the reduction of its nitro precursor, 4-fluoro-2-nitroanisole. This reduction can be achieved through various methods, including catalytic hydrogenation, often employing palladium on carbon as a catalyst, or chemical reduction using agents like zinc in acidic conditions. The choice of reducing agent and reaction parameters significantly influences the yield and purity of the final product. Our manufacturing processes are optimized to ensure high conversion rates and minimal by-product formation, making us a reliable supplier for your critical synthesis needs. When you purchase from us, you're investing in a product synthesized with precision.

Key physical and chemical properties of 4-Fluoro-2-methoxyaniline contribute to its versatility. It typically appears as a yellow to light brown liquid, with a density around 1.176 g/cm³ and a boiling point of approximately 215°C at 756 mmHg. Its refractive index falls within the range of 1.5400 to 1.5440. The compound exhibits weak basicity, with a pKa of about 4.60. These properties are essential for predicting its behavior in various chemical reactions and formulating it into specific applications. For instance, its boiling point and density are critical considerations for process engineers during large-scale production. We ensure that all specifications are clearly communicated to our clients.

For businesses aiming to source this crucial chemical, understanding its market and supply chain dynamics is important. NINGBO INNO PHARMCHEM CO.,LTD. offers a robust supply chain, ensuring that whether you require small quantities for research or bulk orders for industrial production, your needs will be met promptly. We are committed to providing competitive pricing and excellent customer service to all our clients looking to buy 4-Fluoro-2-methoxyaniline. Explore the advantages of partnering with a leading Chinese manufacturer for your chemical intermediate requirements. Contact us for a personalized quote and to learn more about our product offerings.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

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  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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