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Tacrolimus Monohydrate, identified by CAS number 109581-93-3, is a complex macrolide lactam with profound immunosuppressive properties. As a critical compound within the pharmaceutical landscape, understanding its chemical profile is essential for any professional involved in its procurement or application. This article provides a concise overview for those looking to buy Tacrolimus Monohydrate.
Chemically, Tacrolimus Monohydrate is characterized by its intricate structure, with the molecular formula C44H71NO13 and a molecular weight of approximately 822.05 g/mol. It typically appears as a white to almost white powder and exhibits solubility in solvents such as DMSO. Its melting point is recorded between 127-129°C, and its optical rotation (α D23) is -84.4° (c = 1.02 in chloroform). These physical and chemical properties are vital for quality control and formulation.
Commonly known by synonyms such as FK-506, Fujimycin, and Tsukubaenolide, Tacrolimus Monohydrate serves as a potent calcineurin inhibitor. Its primary mechanism of action involves suppressing T-cell mediated immune responses, making it indispensable in preventing organ transplant rejection and managing conditions like atopic dermatitis and certain autoimmune diseases.
For procurement managers and R&D scientists, sourcing this pharmaceutical intermediate requires careful consideration of purity and reliability. When you search for a supplier in China, ensure they can provide documentation such as a Certificate of Analysis (CoA) and Safety Data Sheet (SDS). These documents confirm the product's specifications and safe handling procedures.
The price of Tacrolimus Monohydrate can vary based on purity, quantity, and supplier. As a leading manufacturer, we offer competitive pricing for high-grade Tacrolimus Monohydrate, ensuring that research institutions and pharmaceutical companies can access this critical compound cost-effectively. We encourage you to request a quote for your specific project needs.
Understanding the chemical profile of Tacrolimus Monohydrate is the first step towards successful procurement and application. We are committed to being your trusted source for this essential pharmaceutical raw material, providing both quality products and comprehensive support.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
