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Understanding Tamoxifen Citrate (CAS 54965-24-1): A Chemical Profile

For professionals in the chemical and pharmaceutical industries, a thorough understanding of key compounds is fundamental. Tamoxifen Citrate, with its CAS number 54965-24-1, is a significant pharmaceutical intermediate whose properties and applications warrant detailed examination. This profile aims to provide researchers, procurement managers, and formulators with comprehensive information regarding its chemical characteristics, synonyms, and critical role in drug synthesis.

Chemical Identity and Properties

Tamoxifen Citrate is defined by its chemical formula C26H29NO.C6H8O7 and a molecular weight of 563.70. It is typically presented as a white to off-white powder, a physical characteristic crucial for initial identification and quality assessment. The compound's solubility profile, while noted as slightly soluble in water, is an important consideration for its application in various synthesis processes. Further technical data, such as its boiling point of 665.9 °C at 760 mmHg and a flash point of 356.5 °C, are vital for safe handling and processing, especially in industrial settings.

Synonyms and Nomenclature for Clarity

To ensure clear communication and avoid ambiguity in sourcing and research, Tamoxifen Citrate is known by a variety of synonyms. These include well-recognized trade names and chemical nomenclature variations such as Farmifeno, Oncomox, Tafoxen, Kessar, Tamoxasta, and Tamoxifenum (INN-Latin). The inclusion of terms like 'Tamoxifen citrate (JAN/USP)' highlights its adherence to pharmacopoeial standards, a critical factor for pharmaceutical applications. Understanding this extensive list of synonyms is important when searching databases or communicating with different suppliers, ensuring you are referencing the correct substance.

The Role of Tamoxifen Citrate in Pharmaceutical Manufacturing

As a vital pharmaceutical intermediate, Tamoxifen Citrate serves as a precursor in the synthesis of active pharmaceutical ingredients (APIs). Its availability from reliable manufacturers and suppliers is essential for the uninterrupted production of various medications. For procurement professionals tasked with sourcing this compound, understanding its importance in the drug development pipeline is key. The consistent quality and purity of Tamoxifen Citrate sourced from a reputable manufacturer in China or elsewhere directly influence the efficacy and safety of the final drug product. Therefore, thorough due diligence in selecting a supplier, coupled with a clear understanding of the compound's properties, is crucial for successful drug manufacturing.

In essence, Tamoxifen Citrate (CAS 54965-24-1) is more than just a chemical; it's a critical link in the chain of pharmaceutical innovation and production. Its precise identification, consistent quality, and reliable supply are fundamental for advancing healthcare solutions.

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