Custom Manufacturing, Project Outsourcing, your Trusted Partner from China
The intricacies of cellular signaling pathways are central to understanding and treating complex diseases. Among these, the Transforming Growth Factor-beta (TGF-β) pathway stands out for its broad impact on cell growth, differentiation, apoptosis, and immune modulation. Dysregulation of this pathway is a hallmark of many cancers, driving research into specific inhibitors. Central to this effort is understanding TGF-β kinase inhibition, exemplified by compounds like the one identified by CAS number 700874-72-2.
This compound, commonly referred to as Galunisertib or LY2157299, is a highly potent small molecule inhibitor targeting TGF-β receptor type I (TGF-βRI) kinases, such as ALK5. By selectively blocking these kinases, Galunisertib effectively halts the downstream signaling events that promote tumor progression and immune evasion. Its mechanism of action makes it a valuable asset for researchers investigating cancer biology and developing targeted therapies.
The significance of CAS 700874-72-2 in pharmaceutical R&D cannot be overstated. Its ability to modulate crucial cellular processes has led to its investigation in various clinical trials for cancer treatment. Furthermore, its role in reversing immune suppression within the tumor microenvironment opens doors for combination strategies with immunotherapies, a rapidly advancing field in oncology.
For procurement specialists and research scientists, securing a reliable source for high-quality TGF-β kinase inhibitors is paramount. As a leading manufacturer and supplier based in China, we are dedicated to providing researchers with precisely what they need. We ensure that our Galunisertib (LY2157299) meets high purity standards, enabling accurate and reproducible experimental outcomes. Our role extends beyond mere supply; we aim to be a trusted partner in your research endeavors.
We encourage those involved in cancer research, immunology, and drug development to consider our offerings. Understanding the critical role of TGF-β kinase inhibition, we are committed to making high-quality CAS 700874-72-2 readily available. Please contact us to inquire about purchasing this essential compound and to discuss how our manufacturing capabilities can support your project's success.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
