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2-Chloro-5-chloromethylthiazole (CCMT) is a fascinating organic compound that serves as a critical intermediate in various industrial synthesis processes. Its unique chemical structure, featuring a thiazole ring with chlorine substituents, endows it with specific reactivity that makes it highly valuable, particularly in the agrochemical and pharmaceutical sectors. Understanding its properties is key for chemists and procurement specialists looking to leverage this versatile molecule.
Chemically, CCMT is characterized by its molecular formula C4H3Cl2NS and a molecular weight of 168.04 g/mol. It exists as a yellowish liquid or a white to light yellow solid, with a melting point typically around 29-31°C. This dual state depending on ambient temperature is an important consideration for handling and storage. The compound is soluble in common organic solvents like dichloromethane and chloroform, but largely insoluble in water.
The reactivity of CCMT stems from its chloromethyl group and the thiazole ring, making it an excellent electrophile and a suitable precursor for various coupling and substitution reactions. This reactivity is precisely why it is a preferred intermediate for synthesizing complex active ingredients. For instance, in agrochemical synthesis, it is a cornerstone for creating neonicotinoid insecticides like Thiamethoxam and Clothianidin. The chlorine atoms and the thiazole core are integral to the biological activity of these pesticides.
In the pharmaceutical industry, CCMT's utility is highlighted by its role in producing Ritonavir, an essential component in HIV/AIDS treatment. The synthesis of such complex drug molecules requires intermediates that offer specific chemical handles for precise molecular assembly, a role CCMT fulfills effectively. Its chemical stability under appropriate storage conditions (e.g., in dark, inert atmosphere) ensures its usability over extended periods, which is vital for manufacturers managing inventory.
For those interested in purchasing CCMT, knowing these chemical properties helps in selecting the right supplier and ensuring proper handling and application. Manufacturers like us provide detailed technical data sheets and safety information to support our clients. We offer CCMT with guaranteed high purity, meeting the stringent demands of both pesticide and pharmaceutical production. If you are a researcher or a procurement manager, our commitment as a manufacturer ensures you receive a quality product backed by technical expertise.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
