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For chemists, formulators, and procurement specialists in the chemical industry, a thorough understanding of a compound's properties is crucial for its effective utilization and safe handling. 1-Propanesulfonyl Chloride, identified by its CAS number 10147-36-1, is an organic intermediate with distinct chemical characteristics that dictate its applications and required precautions. Familiarity with these properties ensures optimal results in synthesis and safe laboratory or industrial practices.
The molecular formula of 1-Propanesulfonyl Chloride is C3H7ClO2S, with a molecular weight of approximately 142.60 g/mol. This relatively small organic molecule features a sulfonyl chloride functional group (-SO2Cl) attached to a propyl chain. The sulfonyl chloride group is known for its high reactivity, particularly with nucleophiles. This makes it a valuable electrophilic reagent in a variety of organic reactions, including sulfonylation, where it can react with alcohols, amines, and thiols to form sulfonates, sulfonamides, and sulfonyl thioesters, respectively.
Key physical properties reported for 1-Propanesulfonyl Chloride include its appearance, typically described as a colorless to light yellow liquid. Its boiling point is approximately 78-79 °C at 15 mmHg, and it has a density of around 1.267 g/mL at 25 °C. From a safety perspective, it is classified as corrosive and moisture-sensitive. Exposure to moisture can lead to hydrolysis, producing hydrochloric acid and propanesulfonic acid, which can be hazardous. Consequently, it requires storage under an inert atmosphere, such as nitrogen or argon, in tightly sealed containers, and at cool temperatures (often 2-8°C) to maintain its integrity and prevent decomposition.
When considering the purchase of 1-Propanesulfonyl Chloride, understanding these properties informs the selection of appropriate suppliers. Manufacturers should provide accurate technical data and safety sheets (SDS) detailing these characteristics. For R&D scientists, knowing its reactivity profile allows for precise reaction planning, while procurement managers can ensure proper storage and handling procedures are in place upon receipt. The ability to buy this chemical from reliable manufacturers who clearly communicate these properties is essential for both safety and synthetic success.
In summary, the chemical properties of 1-Propanesulfonyl Chloride (CAS 10147-36-1), including its reactive sulfonyl chloride group, physical state, and sensitivity to moisture, define its utility as an organic intermediate. A thorough grasp of these attributes, obtained from dependable manufacturers and suppliers, is fundamental for anyone involved in its procurement, handling, and application in chemical synthesis.
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