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Understanding the Chemical Properties of 5-[[2-(methylamino)-5-nitroanilino]-5-oxopentanoic acid

For chemists and researchers in the pharmaceutical sector, a thorough understanding of chemical intermediates is crucial for optimizing synthesis processes and ensuring product quality. 5-[[2-(methylamino)-5-nitroanilino]-5-oxopentanoic acid, identified by CAS number 91644-13-2, is a significant intermediate used in the production of Bendamustine hydrochloride. Its chemical characteristics dictate handling, storage, and its suitability for complex organic synthesis.

The molecular formula for this compound is C12H15N3O5, with a molecular weight of 281.265. Typically supplied as a white crystalline powder, its appearance is a key quality indicator for R&D scientists and procurement managers. While the exact melting point can vary slightly between batches, it is generally stored under conditions that preserve its integrity. Reliable manufacturers often specify storage in a cool, dry, and well-closed container, away from moisture and direct light to maintain its stability.

The density is recorded at approximately 1.42 g/cm³, and its boiling point is predicted to be around 582.1 ºC at 760 mmHg. These physical properties are important for process engineers when designing reaction and purification steps. When looking to buy this intermediate, ensuring these specifications are met by the supplier is essential.

As a critical component in Bendamustine synthesis, the purity of 5-[[2-(methylamino)-5-nitroanilino]-5-oxopentanoic acid directly impacts the yield and purity of the final API. Pharmaceutical companies seeking to purchase this compound should prioritize suppliers in China and elsewhere who provide a purity of ≥98%. This commitment to quality from manufacturers ensures that the intermediate performs reliably in downstream applications.

Understanding these chemical and physical properties empowers buyers and chemists to make informed decisions when sourcing this vital pharmaceutical intermediate, contributing to the overall success of their drug development and manufacturing endeavors.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

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  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

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  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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