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Understanding the Chemical Specifications of O-tert-Butyl-L-threonine (CAS 4378-13-6)

For professionals in the chemical, pharmaceutical, and biotechnology sectors, a thorough understanding of chemical specifications is vital for successful procurement and application. O-tert-Butyl-L-threonine, identified by its CAS number 4378-13-6, is a compound whose utility is directly linked to its precise chemical characteristics. As a prominent manufacturer and supplier, we are dedicated to providing materials that meet rigorous quality standards and detailed specifications.

O-tert-Butyl-L-threonine is a derivative of the essential amino acid L-threonine. Its molecular formula is C8H17NO3, and it has a molecular weight of approximately 175.23 g/mol. The defining feature of this compound is the tert-butyl ether group protecting the hydroxyl functional group on the beta-carbon. This protection strategy is crucial for controlled synthesis, particularly in peptide chemistry. The tert-butyl group is known for its stability under a range of reaction conditions typically encountered during peptide elongation, while also being readily removable under specific acidic deprotection protocols. This balance of stability and lability makes O-tert-Butyl-L-threonine a highly sought-after building block.

A critical specification for O-tert-Butyl-L-threonine, especially when used as a pharmaceutical intermediate or in high-throughput screening, is its purity. We ensure that our product achieves a purity of ≥99% (often determined by TLC or HPLC). This high level of purity is essential to prevent side reactions, ensure the integrity of synthesized peptides or drug molecules, and meet regulatory requirements for pharmaceutical applications. When you buy O-tert-Butyl-L-threonine from us, you are assured of a product that has undergone stringent quality control measures.

Other important specifications often include its appearance, typically a white to off-white powder, and its optical activity, usually denoted as [α]D20 = -43 ± 2º (c=1 in H2O). These physical and optical properties are indicators of the compound's identity and enantiomeric purity. Understanding these chemical specifications empowers purchasing managers and R&D scientists to make informed decisions. As a leading manufacturer and supplier in China, we are equipped to provide comprehensive technical documentation, including Certificates of Analysis (CoA), to support your procurement needs. We invite you to request a quote for O-tert-Butyl-L-threonine (CAS 4378-13-6) and experience the quality and reliability of our offerings.

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