Menadione Sodium Bisulfite (CAS 130-37-0) is a compound that bridges the gap between synthetic chemistry and vital biological functions. As a water-soluble derivative of menadione, a synthetic form of Vitamin K, its chemical structure and properties make it an indispensable ingredient in animal nutrition and a crucial intermediate in pharmaceutical synthesis. Understanding its chemistry is key to appreciating its broad utility. As a dedicated chemical manufacturer, we delve into the scientific underpinnings of this compound to ensure its optimal production and application.

Chemically, Menadione Sodium Bisulfite is characterized by its naphthoquinone structure with a bisulfite addition to the methyl group, rendering it soluble in water. The molecular formula is C11H9NaO5S, and its molecular weight is approximately 276.24 g/mol. Its solid form, often an off-white powder, exhibits a melting point typically between 121-124°C. The key functional aspect of this compound is its ability to act as a pro-vitamin K. Once administered, it can be converted in the body to biologically active forms of Vitamin K, primarily menaquinone-4 (MK-4). This conversion is essential for its role in vital physiological processes.

The most well-established application of Menadione Sodium Bisulfite is in the animal feed industry. Vitamin K is indispensable for the post-translational modification of several blood clotting factors (Factors II, VII, IX, and X) through a process called gamma-carboxylation. Without adequate Vitamin K, these factors are not functional, leading to impaired hemostasis and potentially fatal hemorrhages. Thus, Menadione Sodium Bisulfite serves as a reliable source of Vitamin K activity, essential for preventing such conditions in livestock, poultry, and aquaculture. Its water solubility ensures uniform distribution in feed and water, making it highly bioavailable.

Beyond coagulation, Vitamin K also plays a role in bone health by facilitating the carboxylation of osteocalcin, a protein critical for bone mineralization. This further solidifies its importance in animal nutrition, contributing to stronger skeletal development and reduced risk of fractures. For aquaculture, it's also noted for its potential role in stress resistance and immune function.

In the pharmaceutical sector, Menadione Sodium Bisulfite acts as a key intermediate. Its well-defined chemical properties and reactivity make it a suitable starting material for synthesizing more complex pharmaceutical compounds, particularly those targeting coagulation disorders or vitamin K deficiencies. For researchers, it is also used as a tool to induce oxidative stress in cellular models, aiding in the study of cellular damage and repair mechanisms. Its ability to generate reactive oxygen species makes it a valuable reagent in biochemical and biomedical research.

When considering the purchase of Menadione Sodium Bisulfite (CAS 130-37-0), it is crucial to engage with a manufacturer that understands its chemical nuances and application requirements. Our manufacturing process is designed to yield a high-purity product that meets the stringent demands of these diverse industries. We invite R&D scientists and procurement managers to explore our offerings and discuss their specific needs for this versatile chemical. Contact us to get a competitive price and reliable supply.