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Understanding the Chemistry of 2-(Hydroxymethyl)pyridine: A Supplier's Perspective

As a leading manufacturer and supplier of fine chemicals, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing our clients with not only high-quality products but also valuable insights into their chemical properties and applications. Today, we focus on 2-(Hydroxymethyl)pyridine (CAS 586-98-1), a compound that plays a vital role in various synthetic processes. Understanding its chemical nuances is key for any chemist or procurement specialist looking to buy this versatile intermediate effectively.

2-(Hydroxymethyl)pyridine, also known by synonyms such as 2-pyridinemethanol or piconol, is characterized by a pyridine ring substituted with a hydroxymethyl group at the 2-position. The molecular formula is C6H7NO, with a molecular weight of approximately 109.13 g/mol. Its physical appearance is typically described as a colorless to pale yellow liquid, with a melting point around 5.0°C and a boiling point of 220-223°C at atmospheric pressure. These physical properties are important for handling, storage, and reaction setup. For instance, its liquid state at room temperature simplifies handling and dispensing, while its relatively high boiling point indicates good thermal stability under many reaction conditions. When you purchase this chemical, these attributes contribute to ease of use in laboratory and industrial settings.

The reactivity of 2-(Hydroxymethyl)pyridine stems from its bifunctional nature. The pyridine ring, being an aromatic heterocycle, exhibits basic properties due to the lone pair of electrons on the nitrogen atom. This allows it to participate in acid-base reactions, form coordination complexes with metal ions, and undergo electrophilic aromatic substitution under specific conditions, though the ring is generally less reactive than benzene towards electrophiles. The hydroxymethyl group (-CH2OH) is a primary alcohol, which is highly versatile. It can be readily oxidized to an aldehyde or carboxylic acid, esterified with acids or acid chlorides, or etherified. These reactions are fundamental to its use as a building block in organic synthesis. For example, its use as a pharmaceutical intermediate often relies on the selective functionalization of the alcohol group.

As a dedicated supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. ensures that our 2-(Hydroxymethyl)pyridine is produced to high purity standards, typically above 97.5% as per GC analysis. This level of purity is critical for applications where side reactions or contamination can compromise yield and product quality. We also focus on providing competitive price points for bulk orders, understanding that cost-effectiveness is a major consideration for our B2B clients. Whether you are engaged in R&D or large-scale manufacturing, our team is ready to assist you with your procurement needs.

In summary, 2-(Hydroxymethyl)pyridine is a chemically rich intermediate with diverse applications. Its pyridine moiety and reactive alcohol group offer a wide range of synthetic possibilities. NINGBO INNO PHARMCHEM CO.,LTD. is your trusted partner for sourcing high-quality 2-(Hydroxymethyl)pyridine from China, offering excellent value and reliable service. Contact us today to discuss your requirements and to get a quote for your next order.

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