1-Methyl-3-(trifluoromethyl)-1H-pyrazol-5-ol, identified by its CAS number 122431-37-2, is a notable organic compound gaining prominence in various chemical synthesis sectors. Its molecular formula, C5H5F3N2O, and molecular weight of approximately 166.10 g/mol, define its fundamental chemical identity. Typically presenting as a white to off-white crystalline powder or solid, this compound boasts a minimum purity of 98%, making it a dependable choice for precise chemical reactions.

The significance of this pyrazole derivative lies in its strategic placement of functional groups. The trifluoromethyl (CF3) group, a powerful electron-withdrawing moiety, often imparts increased lipophilicity and metabolic stability to molecules. Coupled with the pyrazole ring and the hydroxyl substituent, it creates a versatile building block for complex organic synthesis. Its melting point, typically around 148-152 °C, indicates its solid state under standard conditions.

The primary application of 1-Methyl-3-(trifluoromethyl)-1H-pyrazol-5-ol is as a crucial intermediate in organic synthesis. It serves as a foundational component in the development of specialized chemical entities. In the pharmaceutical industry, it is employed for the synthesis of novel Active Pharmaceutical Ingredients (APIs), where the trifluoromethyl pyrazole motif can enhance drug efficacy and pharmacokinetic profiles. Potential therapeutic areas include anti-inflammatory agents, analgesics, and compounds targeting the central nervous system.

Furthermore, this compound finds significant utility in the agrochemical sector. It acts as a precursor for creating new pesticides, herbicides, and fungicides. The presence of the trifluoromethyl-substituted pyrazole motif is a characteristic feature of several commercial agrochemicals, contributing to their potency and selectivity in protecting crops. Its chemical structure allows for further derivatization to fine-tune biological activity and target specificity.

For businesses seeking to procure this intermediate, identifying reliable manufacturers and suppliers is essential. Companies offering this product often emphasize its high purity, stable storage conditions (cool, dry, and dark place), and its role in both pharmaceutical and agrochemical synthesis. Understanding the product's chemical properties and application scope allows procurement managers and R&D scientists to make informed decisions when sourcing this vital organic synthesis building block. Inquiring about pricing and bulk availability from manufacturers in regions like China can further streamline the procurement process.