In the realm of fine chemicals, understanding the precise properties and applications of intermediates is crucial for chemists, formulators, and procurement managers. 3-Bromo-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one, identified by its CAS number 86499-96-9, is a significant compound primarily utilized in the pharmaceutical industry. As a dedicated supplier of specialized chemical intermediates, we aim to provide clarity on this important molecule.

Chemically, 3-Bromo-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one (C10H10BrNO) has a molecular weight of 240.10 g/mol. It typically appears as a white to off-white crystalline powder, indicating a solid state at room temperature. Its solubility profile shows it is slightly soluble in common organic solvents like ethanol, benzene, and acetone, but it remains insoluble in water. This characteristic is important for its handling during synthesis and purification processes. The melting point is approximately 164 °C, further confirming its crystalline solid nature. While its boiling point is high (around 383.2 °C predicted), it is more commonly handled and reacted in its solid form.

The primary application of this compound is as a key intermediate in the synthesis of Benazepril Hydrochloride. Benazepril is a potent ACE inhibitor, a class of drugs essential for managing cardiovascular conditions such as hypertension. The bromine atom and the specific benzazepinone structure of this intermediate are critical for the subsequent chemical transformations that lead to the formation of the active pharmaceutical ingredient. Pharmaceutical companies looking to buy this intermediate for their Benazepril production can rely on our commitment to high purity and consistent quality.

The preparation and synthesis of 3-Bromo-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one often involve multi-step organic reactions. Common synthetic routes start from readily available materials and proceed through cyclization, bromination, and rearrangement steps. Understanding these synthesis pathways helps in appreciating the value and complexity of this chemical. As a supplier, we ensure that the products we offer are manufactured using optimized and validated processes, contributing to their reliability.

For researchers and industrial chemists, having access to detailed information about chemical intermediates is vital for successful project outcomes. Whether you are developing new synthetic routes or scaling up existing pharmaceutical processes, the availability of high-quality 3-Bromo-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one from a trusted source like ours can significantly impact efficiency and product yield. When considering purchasing this compound, inquire about purity, CAS number verification, and the supplier's capabilities to meet your specific project needs.