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Understanding the Properties and Uses of 4'-Fluorochalcone (CAS 399-10-0)

4'-Fluorochalcone, identified by its CAS number 399-10-0, is a fascinating organic compound that holds significant importance in various scientific and industrial fields. Its unique chemical structure and properties make it a valuable intermediate and building block for a wide array of applications, from pharmaceutical development to the creation of advanced materials.

Physically, 4'-Fluorochalcone typically appears as a light yellow to yellow or even orange powder or crystalline solid. Its melting point is generally reported in the range of 76-82°C, indicating it is a solid at room temperature. The compound has a molecular formula of C15H11FO and a molecular weight of approximately 226.25 g/mol. The presence of a fluorine atom on one of the phenyl rings is a key feature that influences its reactivity and electronic properties, making it distinct from non-fluorinated chalcones. These characteristics are often leveraged by chemists when looking to buy specific reagents for tailored synthesis.

Chemically, 4'-Fluorochalcone is a derivative of chalcone, which is an α,β-unsaturated ketone. This structural motif makes it reactive in various organic transformations. The carbonyl group and the conjugated double bond are sites for nucleophilic addition, Michael addition, and cycloaddition reactions. The fluorine atom, being highly electronegative, can influence the electron density distribution within the molecule, affecting its reaction rates and regioselectivity in certain reactions. For researchers and formulators, understanding these properties is crucial when planning to purchase this compound for specific synthetic purposes.

The applications of 4'-Fluorochalcone are diverse and continue to expand. In the pharmaceutical industry, it serves as a vital intermediate for synthesizing a wide range of biologically active compounds. Derivatives of fluorinated chalcones have demonstrated promising pharmacological activities, including anti-cancer, anti-inflammatory, antioxidant, and antimicrobial effects. This makes it a compound of interest for drug discovery and development. For companies engaged in this sector, securing a reliable manufacturer for high-purity 4'-Fluorochalcone is essential.

Furthermore, 4'-Fluorochalcone plays a role in materials science, particularly in the development of organic electronic materials. Its photophysical properties, such as fluorescence, make it a candidate for use in organic light-emitting diodes (OLEDs), where it can contribute to color tuning and improved device efficiency. The demand for such advanced materials drives the need for specialized chemical building blocks. Therefore, finding a trustworthy supplier who can provide consistent quality and competitive price for 4'-Fluorochalcone is a strategic objective for many research and manufacturing entities.

When considering the acquisition of 4'-Fluorochalcone, paying attention to its CAS number (399-10-0) is critical for accurate identification and sourcing. Engaging with suppliers, especially those offering products from established manufacturers in China, can provide access to this important chemical building block at advantageous terms, enabling further innovation across various scientific disciplines.

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