Custom Manufacturing, Project Outsourcing, your Trusted Partner from China
In the ongoing battle against viral pathogens, understanding the intricate mechanisms of viral replication is paramount. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-quality chemical compounds that empower researchers in this critical field. One such compound is the peptide identified by CAS number 730985-86-1, a vital tool in the study of the SARS coronavirus.
This specialized peptide, known as DABCYL-Lys-HCoV-SARS Replicase Polyprotein 1ab (3235-3246)-Glu-EDANS trifluoroacetate salt, plays a dual role: it acts as a fluorescent substrate and a potent inhibitor of the viral replicase enzyme. Specifically, it targets the 3CLpro enzyme, a crucial component of the SARS-CoV replication machinery. The ability to inhibit this enzyme is a key strategy in the development of antiviral drugs.
The effectiveness of this peptide is underscored by its performance in various scientific studies. Molecular docking simulations have revealed its strong binding affinity to the active site of the 3CLpro enzyme, suggesting a direct mechanism of action. Furthermore, experimental results have confirmed its inhibitory activity, with kinetic analysis yielding a Ki value of 0.7 mM. This demonstrates a significant level of potency, making it a valuable asset for researchers aiming to disrupt viral replication.
The application of this peptide extends to several key areas within virology and pharmacology. As a critical component for viral inspection, it aids in the detailed study of viral processes. Its efficacy as a SARS replicase inhibitor peptide makes it a subject of interest for developing new therapeutic agents. Researchers looking for a reliable 3CLpro enzyme inhibitor will find this compound to be exceptionally useful in their experimental setups.
Furthermore, its utility as a fluorescent substrate opens doors for sensitive detection methods. This allows for precise quantification and monitoring in various biochemical assays. The availability of such a high-purity compound is essential for ensuring the reproducibility and reliability of scientific findings. When considering the purchase of such specialized reagents, the quality and consistency offered by NINGBO INNO PHARMCHEM CO.,LTD. are crucial for successful research outcomes.
The search for effective antiviral solutions is a continuous effort, and compounds like peptide 730985-86-1 are at the forefront of this research. By providing access to these advanced materials, NINGBO INNO PHARMCHEM CO.,LTD. supports the global scientific community in its mission to combat viral diseases and improve public health.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
