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Understanding the Specifications of tert-butyl 6-cyano-2-...-1H-indole-3-carboxylate

For professionals in the pharmaceutical and fine chemical industries, understanding the detailed specifications of chemical compounds is crucial for successful research, development, and manufacturing. Tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate, identified by CAS number 1256584-75-4, is a prime example of a complex intermediate where precise specifications dictate its utility.

This compound, with its molecular formula C25H27IN2O2 and a molecular weight of 514.40 g/mol, is primarily recognized as a key intermediate in the synthesis of Alectinib, a vital oncology drug. The specifications provided by a reputable supplier are critical indicators of its suitability for this purpose. High purity, typically exceeding 95% as determined by HPLC, is non-negotiable. Impurities, even in trace amounts, can interfere with reaction yields, introduce unwanted side effects in the final drug product, or complicate regulatory approval processes.

Beyond purity, other specifications are important for handling and application. While the exact physical form can vary slightly, it is generally described as a solid at room temperature. Safety data, including GHS pictograms and hazard statements (e.g., H302, H315, H319, H335), provides essential information for safe handling and storage. Understanding these aspects is vital for laboratory personnel and production teams.

As a dedicated manufacturer and supplier of tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate, we ensure that all our products come with comprehensive documentation. This includes detailed chemical properties, safety data sheets (SDS), and Certificates of Analysis (COA) that precisely outline the batch-specific specifications. For companies looking to buy this intermediate, requesting this information upfront from a manufacturer like us is a standard practice.

The reliable sourcing of CAS 1256584-75-4 hinges on trusting the supplier's commitment to delivering a product that consistently meets these specifications. We, as a China-based manufacturer, are committed to transparency and quality, making us a preferred partner for pharmaceutical companies worldwide seeking this critical intermediate.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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Address: No.163 Ruiqing Rd.,Ningbo 315000 China
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