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3,5-Di-tert-butylbromobenzene, identified by CAS number 22385-77-9, is a significant compound in the landscape of organic chemistry. Its unique structural features, characterized by the presence of two bulky tert-butyl groups at the meta positions relative to the bromine atom, dictate its reactivity and applications. NINGBO INNO PHARMCHEM CO.,LTD. is involved in providing access to such essential chemical building blocks.
The typical 3,5-Di-tert-butylbromobenzene synthesis involves the electrophilic aromatic substitution, specifically bromination, of 1,3,5-tri-tert-butylbenzene. This method is favored for its ability to introduce the bromine atom regioselectively. The bulky tert-butyl groups help to direct the incoming electrophile to the desired position and also provide steric hindrance, which can influence the subsequent reactions. The optimization of these 3,5-Di-tert-butylbromobenzene synthesis methods is key to achieving high purity, often exceeding 99%, which is critical for its use in demanding synthetic routes.
In terms of reactivity, the bromine atom on the benzene ring is susceptible to nucleophilic displacement or participation in various metal-catalyzed cross-coupling reactions. For instance, the Suzuki-Miyaura coupling, Heck reaction, and Sonogashira coupling are all viable pathways for functionalizing the aromatic core of 3,5-Di-tert-butylbromobenzene. Understanding the 3,5-Di-tert-butylbromobenzene chemical properties, including its electron density distribution and steric environment, allows chemists to predict and control reaction outcomes. This makes it a valuable tool for constructing complex molecules, including those found in pharmaceuticals and advanced materials.
Researchers seeking to buy 3,5-Di-tert-butylbromobenzene online are often looking for a compound that can reliably participate in these advanced transformations. The emphasis on 3,5-Di-tert-butylbromobenzene purity and quality is therefore substantial, as even trace impurities can lead to undesired side reactions or reduced yields. NINGBO INNO PHARMCHEM CO.,LTD. ensures that the products supplied adhere to strict quality controls, providing chemists with the confidence needed to advance their research and development projects.
The availability and predictable reactivity of 3,5-Di-tert-butylbromobenzene underscore its importance as a versatile intermediate in modern chemical synthesis.
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