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Understanding Trifluoroacetamide (CAS 354-38-1): Properties and Applications

Trifluoroacetamide (CAS 354-38-1) is a chemical compound that has garnered significant attention in scientific and industrial communities due to its unique properties and broad applicability. As a white crystalline solid, it presents itself as a readily manageable reagent for a multitude of chemical processes. Understanding its characteristics is crucial for leveraging its full potential in research and manufacturing.

Physically, Trifluoroacetamide typically appears as a white crystal. Its molecular formula is C2H2F3NO, and it has a molecular weight of 113.04. A key attribute that makes it highly desirable for many applications is its high purity, often assaying at ≥99.0%. Furthermore, its low water content, usually ≤0.5%, is critical for reactions that are sensitive to moisture, ensuring predictable outcomes and minimizing unwanted side reactions. These stringent specifications are maintained by reputable manufacturers to guarantee performance in demanding environments.

Chemically, Trifluoroacetamide is recognized for its versatility. It is a key reagent in organic synthesis, playing a vital role in several transformative reactions. One of its most significant applications is in the synthesis of primary amines from precursors like halides or methanesulfonic acids. This transformation is a fundamental pathway for building complex organic molecules. Additionally, Trifluoroacetamide is instrumental in the creation of fluorinated compounds. The incorporation of fluorine atoms can profoundly influence a molecule's properties, leading to enhanced stability, altered reactivity, and improved biological activity, making it invaluable for pharmaceutical and agrochemical development.

The applications of Trifluoroacetamide extend beyond synthesis. It is also employed as a protecting or derivatizing agent in specific chemical pathways. This means it can temporarily mask a functional group, allowing other parts of a molecule to react selectively, and then be cleanly removed. This strategic use is essential in multi-step synthesis where precision is paramount. For those looking to buy Trifluoroacetamide for such purposes, sourcing from a reliable supplier is important to ensure consistent reactivity and purity.

As a highly sought-after chemical, understanding where to procure Trifluoroacetamide is essential. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. provide this compound with a commitment to quality and a deep understanding of its applications. Whether you are engaged in academic research, developing new pharmaceuticals, or formulating advanced materials, Trifluoroacetamide offers a reliable and potent solution. We encourage you to inquire about our Trifluoroacetamide price and availability to support your chemical endeavors.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

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  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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