Valerophenone, known by its CAS number 1009-14-9, is an aromatic ketone that has garnered significant attention in the chemical industry for its diverse applications and utility as a chemical intermediate. This article delves into the fundamental properties, common synthesis routes, and key applications of Valerophenone, offering insights valuable to chemists, researchers, and procurement professionals. As a manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. is well-positioned to discuss the practical aspects of working with this versatile compound.

Valerophenone, also referred to as butyl phenyl ketone or pentanophenone, is an organic compound with the molecular formula C11H14O. Physically, it presents as a clear liquid, often with a slight yellow to yellow-green hue. Its physical characteristics include a melting point of approximately -9°C and a boiling point around 244-245°C. It is notably insoluble in water but soluble in common organic solvents, which is advantageous for many chemical reactions and purification processes. The flash point of Valerophenone is around 102°C (closed cup), indicating it requires careful handling due to its flammability. Its characteristic odor is described as balsamic and reminiscent of valerian root, making it a point of interest in flavor and fragrance research, although its primary industrial uses lie elsewhere.

The synthesis of Valerophenone typically involves established organic chemistry reactions. One common method is the Friedel-Crafts acylation of benzene with valeryl chloride in the presence of a Lewis acid catalyst like aluminum chloride. Another route includes the reaction of methyl benzoate with phenylmagnesium bromide, a Grignard reaction, followed by oxidation. These synthesis pathways are well-documented and allow for industrial-scale production, ensuring a steady supply for global markets. Manufacturers often optimize these processes for yield, purity, and cost-efficiency, making Valerophenone accessible for various applications.

The applications of Valerophenone are multifaceted. In organic synthesis, it serves as a crucial intermediate for the production of a wide array of downstream products, including pharmaceuticals, agrochemicals, and specialty polymers. Its carbonyl group and adjacent alpha-hydrogens provide reactivity points for further functionalization. Furthermore, Valerophenone is widely utilized in photochemical research. Due to its well-defined photochemical behavior, it functions as a UV actinometer – a tool used to measure the intensity of UV light in experimental setups. This is vital for controlling and quantifying light-driven reactions. Additionally, its role as an inhibitor of the enzyme carbonyl reductase is of interest in biochemical studies.

For businesses looking to buy Valerophenone, partnering with a reliable manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. is key. We offer high-purity Valerophenone and are committed to consistent quality and supply. We encourage interested parties to reach out for detailed product information, competitive quotes for bulk purchases, and to request samples to assess its suitability for their specific needs.