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Understanding Valnemulin (CAS 101312-92-9): Properties and Pharmaceutical Applications

Valnemulin (CAS 101312-92-9) is a compound of significant interest in the pharmaceutical industry, particularly within the veterinary sector. As a pleuromutilin antibiotic, it possesses a unique chemical structure and a potent mechanism of action that makes it invaluable for treating a range of bacterial infections. Understanding its properties and applications is key for R&D scientists and procurement specialists seeking high-quality pharmaceutical intermediates.

Chemically, Valnemulin is characterized by its complex polycyclic structure. It typically presents as a white solid, with a melting point commonly reported between 140-143°C. Its solubility profile indicates it is soluble in common organic solvents like ethanol, methanol, DMF, and DMSO, which is a crucial consideration for formulation development and manufacturing processes. This solubility allows for easier integration into various dosage forms, whether for oral administration in feed premixes or other veterinary applications.

The primary application of Valnemulin lies in its potent antibacterial activity. It functions by inhibiting bacterial protein synthesis, a critical process for bacterial survival. This makes it highly effective against a variety of Gram-positive bacteria, as well as certain fastidious Gram-negative bacilli and mycoplasmas. Its established efficacy in treating conditions like swine dysentery, ileitis, colitis, and pneumonia in livestock, especially pigs, has cemented its role as a vital veterinary pharmaceutical. Manufacturers aiming to buy Valnemulin can leverage these established applications.

For those involved in the procurement of pharmaceutical ingredients, sourcing Valnemulin with high purity is non-negotiable. Impurities can affect efficacy, safety, and regulatory compliance. Reputable suppliers, often based in regions with strong chemical manufacturing capabilities like China, offer Valnemulin with assured purity levels, typically above 99% by HPLC. These manufacturers provide detailed documentation, including Certificates of Analysis, to verify product quality, which is essential for R&D and bulk purchase orders.

The commercial aspect of Valnemulin involves its availability from various manufacturers and suppliers. When seeking to purchase Valnemulin, engaging with suppliers who can provide a quote for bulk quantities is a standard practice. These suppliers can also offer insights into transportation, packaging, and delivery options, ensuring that the product reaches its destination safely and efficiently. The molecule's CAS number, 101312-92-9, serves as a universal identifier, streamlining the inquiry and procurement process.

In essence, Valnemulin is a critical pharmaceutical intermediate with well-defined chemical properties and significant applications in veterinary medicine. Its effectiveness against bacterial infections in livestock makes it a high-demand product. For any organization looking to acquire Valnemulin, partnering with a reliable manufacturer and supplier that guarantees purity and consistent supply is fundamental to success.

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