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Vinblastine Sulfate, identified by CAS number 143-67-9, is a compound of significant interest in both pharmaceutical research and clinical oncology. This natural alkaloid, derived from the periwinkle plant, functions as a potent antineoplastic agent by disrupting microtubule dynamics within cells. NINGBO INNO PHARMCHEM CO., LTD. supplies this vital chemical intermediate, enabling advancements in cancer therapy and related research.
Chemically, Vinblastine Sulfate is a white to off-white crystalline powder, characterized by its solubility in water and methane, and slight solubility in ethanol. Its high purity, typically exceeding 99%, is a testament to meticulous manufacturing processes. The compound's molecular weight is approximately 909.07 g/mol, with the empiric formula C46H58N4O9.H2SO4. Its physical form and chemical stability are crucial for its application as a pharmaceutical intermediate.
The mechanism of action for Vinblastine Sulfate is deeply rooted in its interaction with tubulin, the protein subunit of microtubules. By binding to tubulin, it inhibits the polymerization of microtubules, which are essential for forming the mitotic spindle during cell division. This disruption leads to the arrest of cells in the metaphase stage of mitosis, a process known as stathmokinesis. This targeted action is what makes Vinblastine Sulfate an effective antineoplastic agent, crucial in cancer treatment protocols.
Therapeutically, Vinblastine Sulfate is employed in the treatment of various cancers, including Hodgkin's disease, non-Hodgkin's lymphoma, mycosis fungoides, advanced testicular carcinoma, and Kaposi sarcoma. It is also utilized in managing choriocarcinoma and certain types of leukemia. The ability to buy Vinblastine Sulfate from reliable sources like NINGBO INNO PHARMCHEM CO., LTD. ensures that healthcare providers have access to this critical medication. Further research continues to explore its biological activity, including its role in inducing apoptosis in cultured cells, underscoring its importance in ongoing cancer research.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
