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Unlock DNA Purity: The Essential Role of Proteinase K in Extraction

In the intricate world of molecular biology, the purity of extracted DNA and RNA is paramount for the success of downstream applications. One of the unsung heroes in this process is Proteinase K. As a premier manufacturer and supplier based in China, we understand the critical need for high-quality biochemical reagents, and our Proteinase K stands as a testament to this commitment.

Proteinase K, a serine protease derived from the fungus Tritirachium album, is renowned for its broad specificity. It functions by cleaving peptide bonds adjacent to aliphatic and aromatic amino acids, making it exceptionally effective at degrading a wide range of proteins. This broad action is precisely why it is indispensable during nucleic acid extraction. When you buy Proteinase K from a reputable supplier, you are investing in the integrity of your genetic material.

The primary role of Proteinase K in DNA and RNA isolation is to efficiently remove contaminating DNases and RNases. These endogenous enzymes, if left unchecked, can rapidly degrade your precious DNA and RNA targets, rendering them useless for further analysis such as PCR, sequencing, or cloning. By adding Proteinase K to your lysis buffer, you effectively inactivate these nucleases, ensuring that your nucleic acids remain intact and of high molecular weight. This makes us a key supplier for researchers focused on obtaining pure genetic material.

Furthermore, Proteinase K also digests histones and other DNA-binding proteins that can hinder DNA accessibility. Its remarkable stability in the presence of common lysis reagents like SDS (sodium dodecyl sulfate) and EDTA (ethylenediaminetetraacetic acid) further enhances its utility. Unlike many other proteases, Proteinase K retains significant activity even in 1% SDS or 0.5% SDS, and it is not readily inhibited by metal chelating agents. This robustness makes it a versatile tool for various extraction protocols, especially those involving challenging sample matrices.

For procurement professionals and research scientists seeking a reliable Proteinase K price, our company, a leading manufacturer in China, offers competitive solutions. We ensure that our Proteinase K, presented as a white powder, meets stringent quality specifications, including an assay of ≧95% and an activity of 30.0-45.0 u/mg. This consistent quality translates directly into reproducible results in your laboratory.

Choosing the right Proteinase K supplier is a strategic decision. We are dedicated to providing not just a product, but a solution that supports your scientific endeavors. Whether you are preparing chromosomal DNA for pulsed-field gel electrophoresis, performing protein fingerprinting, or simply aiming for the cleanest possible nucleic acid preparations, our Proteinase K is your trusted partner. Inquire today about purchasing high-purity Proteinase K and experience the difference that quality and expertise from a dedicated manufacturer can make.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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WHY CHOSE US?

1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

CONTACT US
Should you need to contact us; you may call during regular business hours, Monday through Friday, 8am – 6 pm.
NINGBO INNO PHARMCHEM CO.,LTD.
Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
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