Minoxidil Powder, identified by CAS number 38304-91-5, stands as a significant active pharmaceutical ingredient. This substance presents as a white or off-white crystalline powder with a purity typically exceeding 99%. It is widely recognized for its dual applications, historically in managing hypertension and more recently, and perhaps more popularly, in addressing hair loss concerns.

Originally utilized as an oral medication for refractory hypertension, Minoxidil functions primarily as a powerful vasodilator. Its mechanism in this regard involves acting as a potassium channel opener. By increasing potassium ion permeability, it leads to hyperpolarization of vascular smooth muscle cells, causing relaxation and subsequent dilation of small arteries. This action effectively reduces peripheral vascular resistance and lowers blood pressure. While effective for hypertension, this application has largely been superseded by other antihypertensive agents.

The serendipitous discovery of hair growth as a side effect during its oral administration led to its investigation and subsequent approval for treating androgenetic alopecia, commonly known as pattern baldness. The mechanism by which topical Minoxidil stimulates hair growth is multifaceted and continues to be researched, but key pathways have been identified.

Firstly, Minoxidil Powder is known to directly stimulate the proliferation and differentiation of hair follicle epithelial cells. Studies indicate that even at micro-molar concentrations, it can promote the growth phase of hair follicles. Secondly, it plays a crucial role in promoting angiogenesis, the formation of new blood vessels. Adequate blood supply to the hair papilla is vital for nourishing the hair follicle and supporting healthy hair growth. Minoxidil's ability to enhance local blood flow contributes significantly to its efficacy in promoting hair regrowth.

Furthermore, its function as a potassium channel opener is also implicated in its hair growth effects. By influencing ion channels within hair follicle cells, it is thought to counter inhibitory factors and prolong the anagen (growth) phase of the hair cycle.

High-purity Minoxidil Powder (CAS 38304-91-5) is the essential raw material required for the production of various topical hair growth formulations, including solutions and foams. Its consistent quality is paramount for ensuring the safety and efficacy of the final product. Handling and storage require adherence to recommended conditions, typically storing the powder at room temperature, though formulations may have different requirements.

For pharmaceutical companies, cosmetic manufacturers, and researchers seeking this critical API, sourcing from a reliable manufacturer and supplier is crucial. The availability of high-quality Minoxidil Powder meeting stringent standards is essential for developing effective anti-hair loss and potential antihypertensive products.

Clients interested in the price of high-purity Minoxidil Powder (CAS 38304-91-5) or looking to buy/purchase this raw material in various quantities can inquire directly with reputable sources. Ensuring the supplier adheres to rigorous quality control processes from raw material procurement to the finished product guarantees confidence in the material's integrity. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality active pharmaceutical ingredients like Minoxidil Powder to meet global demands.