The pharmaceutical industry constantly strives for innovation, developing complex medications that address critical health challenges worldwide. Central to this endeavor is the meticulous synthesis of active pharmaceutical ingredients (APIs), a process that heavily relies on high-quality pharmaceutical intermediates. These specialized chemical compounds serve as indispensable building blocks, guiding the precise construction of therapeutic molecules.

One such vital intermediate is (R)-3-Aminobutan-1-ol, a chiral compound with the CAS No. 61477-40-5. It is known by various synonyms including (3R)-3-Amino-1-butanol. This particular intermediate plays a pivotal role in the synthesis of Dolutegravir, an anti-HIV medication. The intricate nature of drug synthesis necessitates intermediates that not only provide structural scaffolding but also ensure the desired stereochemical purity, a critical factor for the biological activity and safety of many modern drugs.

As a key pharmaceutical intermediate, (R)-3-Aminobutan-1-ol exhibits well-defined physical and chemical properties. It typically appears as a colorless clear liquid with a density of approximately 0.9 g/cm3. Its molecular formula is C4H11NO, resulting in a molecular weight of 89.136. Key characteristics also include a boiling point of 168.3±13.0 °C at 760 mmHg and a flash point of 55.6±19.8 °C. Such precise physical parameters are crucial for controlled reactions during API manufacturing.

The quality specifications for (R)-3-Aminobutan-1-ol are stringent to ensure its suitability for pharmaceutical applications. Reputable manufacturers adhere to high purity standards, with an assay (GC) typically greater than or equal to 99.0%. Critically, the purity of enantiomorphism isomers is kept extremely low, at less than or equal to 0.1%, underscoring its precise chiral nature. Furthermore, total impurities are strictly controlled to below 1.0%, with any other individual impurity not exceeding 0.25%. A moisture content of less than or equal to 1.0% is also maintained to preserve its integrity and reactivity.

The application of (R)-3-Aminobutan-1-ol as an intermediate for Dolutegravir (CAS: 1051375-16-6) highlights its significance in the fight against HIV. Dolutegravir is a potent integrase inhibitor, a class of antiretroviral drugs used in the treatment of HIV infection. The chirality of (R)-3-Aminobutan-1-ol is paramount here, as the specific three-dimensional arrangement of atoms is often essential for the drug to bind effectively to its biological target and exert its therapeutic effect with minimal side effects. The reliability and consistency of this intermediate directly translate to the effectiveness and safety of the final medication, impacting countless patient lives globally.

For pharmaceutical companies engaged in the development and production of such life-saving drugs, partnering with a dependable manufacturer and supplier of high-quality pharmaceutical intermediates is non-negotiable. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing premium-grade (R)-3-Aminobutan-1-ol, ensuring it meets the rigorous demands of the pharmaceutical industry. We understand that the integrity of raw materials and intermediates is fundamental to the final product's success and regulatory compliance. Our dedication to quality control and advanced manufacturing processes ensures that every batch maintains consistent purity and specifications, facilitating seamless integration into your synthesis pathways.

When considering the price and seeking to buy or purchase (R)-3-Aminobutan-1-ol, it is essential to prioritize suppliers who can offer not only competitive pricing but also unwavering quality and reliability. NINGBO INNO PHARMCHEM CO.,LTD. offers flexible packaging options, including 200 kg drums, and can tailor packaging to specific customer requirements. We also provide clear guidance on optimal storage conditions—a cool, ventilated place—to maintain product stability over time. As a leading manufacturer and supplier of pharmaceutical intermediates, NINGBO INNO PHARMCHEM CO.,LTD. stands ready to support your complex drug development needs with an assured supply of high-quality (R)-3-Aminobutan-1-ol.