In the intricate landscape of pharmaceutical synthesis, certain chemical intermediates stand out due to their pivotal role in producing life-saving medications. Among these, (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate, identified by its unique CAS number 125971-94-0, is a compound of immense significance. This high-purity chemical serves as a crucial building block in the creation of atorvastatin calcium, a widely recognized and essential lipid-lowering drug. Its precise stereochemistry and purity are paramount for the efficacy and safety of the final pharmaceutical product.

Chemically, (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate boasts a molecular formula of C14H23NO4 and a molecular weight of 269.34. It typically presents as a white to off-white crystalline powder, a testament to its refined state. Quality assurance is critical, with a typical assay of greater than or equal to 98.5% purity. Furthermore, its melting point ranges from 64°C to 70°C, providing additional indicators of its consistent quality. These stringent specifications ensure that the intermediate meets the rigorous demands of pharmaceutical manufacturing processes, where even minor impurities can have significant consequences.

The primary application of CAS 125971-94-0 lies in its role as a key intermediate for the synthesis of atorvastatin calcium. Atorvastatin is a powerful HMG-CoA reductase inhibitor, widely prescribed to reduce high cholesterol levels and prevent cardiovascular diseases such as heart attacks and strokes. Given the widespread prevalence of these conditions, the demand for atorvastatin remains consistently high globally. The specific chiral purity and structural integrity of (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate are essential for achieving the desired stereoselectivity and yield in atorvastatin production, making it an indispensable component in this life-saving drug's chemical pathway.

For pharmaceutical companies and active pharmaceutical ingredient (API) manufacturers, securing a reliable supply of high-quality intermediates like CAS 125971-94-0 is non-negotiable. Consistency in batch quality, adherence to strict analytical standards, and dependable delivery are crucial for maintaining production schedules and ensuring the integrity of the final drug product. A professional chemical manufacturer understands these critical requirements, employing rigorous quality control protocols from raw material sourcing to final product packaging. This dedication to excellence ensures that every batch supplied is of the highest standard, mitigating risks for downstream processes.

Prospective buyers seeking a reputable manufacturer and supplier of (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate, CAS 125971-94-0, should prioritize partners with established expertise in pharmaceutical intermediates. When considering to buy or purchase this essential compound, it is vital to inquire about detailed product documentation, including Certificates of Analysis, Material Safety Data Sheets (MSDS), and any relevant regulatory support. Competitive price points are important, but should always be balanced with assurances of unparalleled quality and consistent supply. For bulk orders, the product is typically packaged in durable 25kg fiber drums, ensuring safe transport and storage. Proper storage conditions, such as a ventilated, low-temperature, dry environment, separated from acids, oxidizers, and food additives, are crucial for maintaining product integrity over time.

As a leading producer dedicated to advanced pharmaceutical intermediates, we are committed to providing the highest quality (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate. Our focus on purity, consistency, and reliable logistics makes us a trusted partner in the pharmaceutical supply chain. For those looking to obtain this critical raw material for atorvastatin calcium synthesis, we invite you to reach out for more information, product documents, or to discuss your specific procurement needs. Partnering with a proven expert ensures that your production processes benefit from superior chemical building blocks.