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Unlocking Chemical Synthesis: The Role of 5-Fluoro-2-methylpyridine

5-Fluoro-2-methylpyridine, identified by its CAS number 31181-53-0, stands as a crucial compound in the realm of advanced organic chemistry. Also known by its synonyms such as 6-methyl-3-fluoropyridine, 5-fluoro-2-picoline, or 3-fluoro-6-methylpyridine, this versatile chemical serves as a fundamental building block for a multitude of synthetic pathways. Its unique molecular structure, represented by the formula C6H6FN and a molecular weight of approximately 111.12, endows it with specific reactivity that makes it indispensable for various industrial and research applications.


Chemically, 5-Fluoro-2-methylpyridine is characterized as a colorless to light yellow liquid. Its physical properties are well-defined, contributing to its handling and application. It possesses a density of 1.077 grams per cubic centimeter. The boiling point typically ranges between 114.7°C at standard pressure and up to 136°C, indicating its volatility. With a flash point recorded at 23.1°C, appropriate safety measures are vital during its storage and use. Maintaining its integrity and purity is paramount, which necessitates storage in a tightly closed container, in a cool and dry environment, ideally under an inert gas atmosphere and at controlled temperatures, such as 2-8°C or even -20°C, depending on specific requirements and desired shelf life.


The primary application of 5-Fluoro-2-methylpyridine lies in its role as an organic intermediate. This means it is not typically a final product but rather a critical precursor used in the synthesis of more complex molecules. Its pyridine ring, combined with the fluorine and methyl substituents, offers unique opportunities for chemical reactions, including nucleophilic aromatic substitutions, metallation reactions, and cross-coupling reactions. These properties make it highly valuable in the creation of pharmaceuticals, agrochemicals, and specialized fine chemicals. Its contribution to drug discovery and material science underscores its importance as a high-purity reagent in demanding synthetic processes.


For laboratories and industries seeking this essential chemical, the quality and consistency of 5-Fluoro-2-methylpyridine are critical. Products are typically offered with a high purity, often exceeding 97.0% and reaching up to 99.0% or higher, ensured through stringent quality control measures. Reputable suppliers focus on delivering material that meets rigorous specifications to facilitate reliable and efficient synthesis. When considering where to buy 5-Fluoro-2-methylpyridine, it is advisable to engage with experienced chemical manufacturers who can provide comprehensive technical data and certificates of analysis.


Sourcing directly from a specialized manufacturer of 5-Fluoro-2-methylpyridine ensures access to consistent batches and competitive pricing. Prospective buyers should inquire about bulk purchasing options to optimize their supply chain. While specific price points vary based on quantity and market conditions, establishing a relationship with a reliable supplier is key for long-term needs. Whether for research and development or large-scale industrial production, a trusted partner can provide the necessary support for your purchase of 5-Fluoro-2-methylpyridine, ensuring timely delivery and adherence to international quality standards.

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