Idebenone, an organic compound with the molecular formula C19H30O5, presents as a yellow crystal or crystalline powder, characterized by its odorless nature. Initially developed and marketed by Takeda Pharmaceutical Co., Ltd. in Japan in 1986, it has since been recognized for its potent therapeutic and cosmetic applications. Chemically, Idebenone belongs to the quinone family and is often promoted as a synthetic analog of coenzyme Q10 (CoQ10), sharing similar antioxidant properties.
At its core, Idebenone functions by activating mitochondrial processes, thereby significantly improving brain metabolism and addressing brain dysfunction. It enhances the brain's utilization of glucose and actively promotes ATP production, which is crucial for cellular energy. Furthermore, it improves the metabolism of the neurotransmitter serotonin in the brain and exhibits strong antioxidant capabilities, making it highly effective in scavenging free radicals. In cellular and tissue models, Idebenone acts as a vital transporter in the electron transport chain of mitochondria, inhibiting lipoperoxide formation and positively impacting the energy balance of mitochondria.
The pharmaceutical applications of Idebenone Powder are diverse and significant. It is primarily used in the clinical treatment of oxidative stress-related central nervous system degenerative diseases, including Parkinson's disease, Alzheimer's disease, multi-infarct dementia, cerebral anemia, and cerebral failure. Research has indicated that Idebenone can improve learning and memory in experimental settings and may offer a slight benefit in Alzheimer's disease by slowing the decline of thinking skills, especially in moderately severe cases. It has also shown promise in treating Leber's Hereditary Optic Neuropathy (LHON), an inherited disorder causing vision loss, where it appears to improve vision. For conditions like Duchenne Muscular Dystrophy (DMD), Idebenone has demonstrated the potential to improve airway function and prevent respiratory complications. While its efficacy for Friedreich's ataxia has been explored, findings have been inconsistent, though some studies suggest a positive effect on cardiac hypertrophy and neurological function, particularly in younger patients.
Beyond its medicinal uses, Idebenone has found a prominent place in cosmetic formulations. Its powerful antioxidant and free radical scavenging properties make it an invaluable ingredient in anti-aging products. It works to inhibit lipid peroxidation, reduce inflammation, protect against DNA damage, and decrease pigmentation, making it an effective topical agent for treating wrinkles and combating the signs of photodamaged skin. Its ability to shield a wide variety of cells from oxidative damage underpins its versatility in both health and beauty sectors.
NINGBO INNO PHARMCHEM CO.,LTD. supplies high-purity Idebenone Powder, typically boasting over 99% purity, ensuring top-tier quality for various applications. With a shelf life of two years when stored properly, this yellow powder is suitable for adult use and available for customization to meet specific needs. For those looking to buy high-purity Idebenone Powder, it's essential to source from a reliable manufacturer. Finding a trusted supplier ensures the quality and efficacy of the product. Information regarding price and bulk purchase options can typically be obtained directly from leading suppliers of pharmaceutical intermediates and cosmetic raw materials.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.