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Unlocking New Syntheses: (6-fluoropyridin-3-yl)boronic Acid (CAS 351019-18-6)

(6-fluoropyridin-3-yl)boronic acid, identified by its CAS No. 351019-18-6, stands as a cornerstone in modern organic synthesis, particularly within the pharmaceutical industry. This highly versatile boronic acid derivative is recognized for its crucial role as a building block in the creation of complex molecular structures. Its unique combination of a pyridine ring, a fluorine atom, and a boronic acid group grants it exceptional reactivity, making it indispensable for a wide array of synthetic transformations in various research and industrial settings.


Chemically, (6-fluoropyridin-3-yl)boronic acid possesses the molecular formula C5H5BFNO2 and a molecular weight of 140.91. It typically appears as a white to light yellow solid, a testament to its inherent purity. With an EINECS number of 627-412-9, this compound is also known by several synonyms, including 6-Fluoropyridine-3-boronic acid, 2-Fluoro-5-pyridineboronic acid, and 6-Fluoropyridin-3-ylboronic acid, reflecting its varied naming conventions across the scientific community. Its melting point generally falls within the range of 172-178°C (with decomposition), further characterizing its significant physical properties and stability.


The primary application of (6-fluoropyridin-3-yl)boronic acid lies in its utility as a pharmaceutical raw intermediate and a versatile building block for synthesis materials intermediates. It is extensively employed in various cross-coupling reactions, most notably the Suzuki-Miyaura coupling, where it efficiently facilitates the formation of carbon-carbon bonds. This reaction is paramount in the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals, enabling the construction of intricate molecular frameworks with high efficiency and selectivity. The presence of its fluorine atom can impart specific desirable properties, such as enhanced metabolic stability or improved bioavailability, to target molecules, making this compound particularly valuable in modern drug discovery and development programs.


As a dedicated manufacturer and supplier of premium chemical compounds, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing (6-fluoropyridin-3-yl)boronic acid of exceptional quality. We adhere to stringent quality control measures throughout our advanced manufacturing processes, ensuring that our product consistently meets and often exceeds industry standards, typically achieving a purity of 97% or higher. Our robust production capabilities allow us to offer this critical intermediate in bulk quantities, guaranteeing a reliable and consistent supply to meet the diverse needs of our global clientele, from small-scale laboratory research to large-scale industrial production.


For researchers and industries looking to buy or purchase high-quality (6-fluoropyridin-3-yl)boronic acid, NINGBO INNO PHARMCHEM CO.,LTD. stands as a trusted partner. We pride ourselves on offering this essential chemical at a highly competitive price, coupled with efficient logistics and dedicated customer support. Our aim is to facilitate your synthetic endeavors by providing a product that performs reliably, ensuring the success and efficiency of your projects in various chemical applications.


Proper handling and storage are paramount to maintaining the integrity and shelf-life of (6-fluoropyridin-3-yl)boronic acid. It is recommended to store the compound in a cool, dry, dark place, keeping the container tightly closed when not in use, to prevent degradation and ensure its stability over time. While generally safe when handled correctly, safety data sheets should always be consulted for detailed information on personal protective equipment and emergency procedures, as it can cause skin and eye irritation and may be harmful if swallowed or inhaled.


In conclusion, (6-fluoropyridin-3-yl)boronic acid (CAS: 351019-18-6) is an indispensable compound for advanced chemical synthesis across various industries. NINGBO INNO PHARMCHEM CO.,LTD. remains your reliable source for this high-purity chemical, ready to support your most challenging projects with superior products and unparalleled service.

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