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Unlocking Pharmaceutical Innovation with 2,2-Dimethylthiopropionamide (CAS 630-22-8)

2,2-Dimethylthiopropionamide (CAS 630-22-8) stands as a pivotal organic intermediate in the chemical and pharmaceutical industries. With its unique molecular structure, C5H11NS, and a molecular weight of 117.21 g/mol, this compound is indispensable for a wide array of synthesis applications.


Characterized as a white powder or solid, 2,2-Dimethylthiopropionamide exhibits a melting point typically ranging from 117°C to 119°C. Its solubility profile includes good solubility in water (approximately 10 g/L at 25°C), chloroform, and ethyl acetate, making it versatile for various reaction conditions. At NINGBO INNO PHARMCHEM CO.,LTD., we ensure a high assay of this compound, consistently achieving purity levels of ≥99.0%, which is critical for demanding pharmaceutical and research applications.


The utility of 2,2-Dimethylthiopropionamide extends across several critical areas. Primarily, it functions as a vital building block in pharmaceutical synthesis. One significant application is its role as a reagent in the synthesis of Dabrafenib, a potent inhibitor of BRAF kinase. Dabrafenib is a crucial medication used in the treatment of specific BRAF V600-mutation positive carcinomas, highlighting the compound's direct impact on advanced medical therapies.


Beyond its use in oncology, 2,2-Dimethylthiopropionamide is also employed in the preparation of sulfonyl-substituted 4,5-diarylthiazoles. These compounds are recognized for their activity as cyclooxygenase-2 (COX-2) inhibitors, which are a class of non-steroidal anti-inflammatory drugs (NSAIDs) widely used for managing pain and inflammation. This dual functionality underscores its importance in both cutting-edge cancer research and general anti-inflammatory drug development. Its versatility also makes it a valuable reagent in general organic synthesis and various research endeavors, particularly in neurological research related to pain and inflammation pathways.


At NINGBO INNO PHARMCHEM CO.,LTD., we understand that the integrity and purity of chemical intermediates are paramount. Our 2,2-Dimethylthiopropionamide is produced under stringent quality control measures to ensure it meets the highest standards required for sensitive applications. Proper storage is essential to maintain its stability and efficacy; it should be kept in a clean, dry, and cool place, shielded from direct sunlight and moisture to preserve its chemical properties over time.


As a dedicated manufacturer and supplier of high-quality chemical intermediates, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing reliable access to essential compounds like 2,2-Dimethylthiopropionamide. For those looking to buy 2,2-Dimethylthiopropionamide or seeking a competitive price, our team is ready to assist with your requirements. We offer flexible packaging options customized to client needs, ensuring secure and efficient delivery. Whether you are looking to purchase 2,2-Dimethylthiopropionamide for research, development, or large-scale production, partner with us for a seamless procurement experience. Our expertise and robust supply chain make us an ideal choice for your chemical sourcing needs.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

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