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Unlocking Potential: 2-Bromo-5-Chloro-1,3-Thiazole (CAS 16629-15-5) as a Core Building Block

2-bromo-5-chloro-1,3-thiazole (CAS: 16629-15-5) stands as a highly significant and versatile chemical intermediate in the realm of organic synthesis. This halogenated thiazole derivative is prized for its unique structural features, which enable it to serve as a crucial building block for creating a wide array of more complex and functionalized molecules. Its strategic placement of bromine and chlorine atoms on the thiazole ring provides excellent opportunities for further chemical modifications, making it indispensable in advanced chemical research and industrial applications.


Chemically, 2-bromo-5-chloro-1,3-thiazole possesses the molecular formula C3HBrClNS and a molecular weight of approximately 198.47 g/mol. It is typically observed as a colorless to light yellow liquid at ambient temperature, characterized by a density of about 1.979 g/cm3. The compound exhibits a boiling point around 216.7ºC at 760 mmHg and a flash point of 84.8ºC, indicating its thermal properties. Its refractive index is approximately 1.622. These well-defined physical and chemical parameters underscore its stability and predictable behavior in various synthetic processes, making it a reliable component for demanding chemical reactions.


The primary utility of 2-bromo-5-chloro-1,3-thiazole lies in its broad applications as a pivotal intermediate, particularly within the pharmaceutical and agrochemical industries, as well as in the development of specialized organic compounds. Its bromo and chloro substituents offer distinct reactivity profiles, allowing for selective functionalization through processes such as Suzuki coupling, Sonogashira coupling, and other cross-coupling reactions. This enables chemists to efficiently construct novel heterocyclic systems and complex molecular scaffolds that are often critical for the development of new active pharmaceutical ingredients (APIs), crop protection agents, and advanced materials.


At NINGBO INNO PHARMCHEM CO.,LTD., we are dedicated to supplying high-purity 2-bromo-5-chloro-1,3-thiazole (CAS: 16629-15-5) that meets the stringent requirements of the global chemical industry. Our manufacturing processes adhere to rigorous quality control standards, ensuring that every batch delivers consistent purity, typically 95% or higher, and optimal performance for your research and production needs. We understand the critical role that quality intermediates play in successful chemical synthesis, and our commitment is to provide products that facilitate innovation and efficiency for our clients worldwide.


As a leading manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. maintains substantial inventory and flexible packaging options to accommodate diverse client requirements, ranging from small research quantities (e.g., 5g, 25g, 100g, 500g, 1kg) to larger industrial volumes (e.g., 25kg). Our competitive price structure and efficient logistics ensure that you receive your product promptly and economically. For those looking to buy or purchase this essential building block, NINGBO INNO PHARMCHEM CO.,LTD. offers a seamless and reliable procurement experience. Our team is readily available to provide detailed product specifications, safety data sheets, and personalized quotes to assist with your specific needs. We invite you to explore our comprehensive product offerings and experience the professionalism and quality that define our service.


Regarding safety, 2-bromo-5-chloro-1,3-thiazole requires careful handling. It is classified with hazard statements such as H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation), and can be Harmful if swallowed (H302). Appropriate personal protective equipment and good laboratory practices are essential during its use. For optimal storage, it is recommended to keep the container closed when not in use and store it in a cool, dry, well-ventilated area, away from incompatible substances, ideally under an inert gas atmosphere at 2-8 °C to maintain its integrity and reactivity over time.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
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