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Unveiling the Health Potential of (S)-3-(Allylsulphinyl)-L-alanine (Alliin)

For millennia, garlic (Allium sativum) has been revered not only as a culinary staple but also as a powerful medicinal agent across diverse cultures, from ancient Egyptians and Chinese to the Greeks and Romans. Central to garlic's remarkable properties is (S)-3-(Allylsulphinyl)-L-alanine, commonly known as Alliin or S-allyl-L-cysteine sulfoxide (CAS: 556-27-4). While Alliin is famously recognized as the precursor to Allicin, the compound responsible for garlic's pungent aroma and some immediate effects, Alliin itself possesses significant biological activity and is considerably more stable, making it an invaluable compound for various applications.


Chemically, (S)-3-(Allylsulphinyl)-L-alanine has the molecular formula C6H11NO3S and a molecular weight of 177.22. It typically appears as a solid and is known for its purity. Unlike the highly unstable Allicin, Alliin is a water-soluble organosulfur compound that maintains its integrity, even in commercial garlic products. This inherent stability ensures its efficacy when incorporated into health and pharmaceutical formulations, providing a reliable active ingredient with consistent performance.


Research has extensively highlighted Alliin's impressive array of health benefits, particularly its positive impact on cardiovascular health. Studies indicate its ability to promote modest but significant lipid-lowering effects, helping to reduce total cholesterol, low-density lipoprotein (LDL) cholesterol, and triglyceride levels. Furthermore, Alliin exhibits antiplatelet activity, which contributes to reducing the risk of blood clot formation. Some evidence also suggests a role in blood pressure regulation and protection against atherosclerosis, supporting overall heart function.


Beyond cardiovascular benefits, (S)-3-(Allylsulphinyl)-L-alanine is celebrated for its potent antimicrobial and antioxidant properties. It has been shown to exert broad-spectrum activity against various pathogens, including bacteria (even antibiotic-resistant strains like MRSA), viruses, fungi (such as Candida albicans), and parasites. Its antioxidant capabilities are crucial, as Alliin effectively reduces oxidative stress and helps protect cells and brain tissue from damage, contributing to anti-aging effects and overall cellular health.


Emerging research also points to Alliin's critical role in metabolic regulation. Studies, particularly in diet-induced obese mouse models, have demonstrated its hypoglycemic and hypolipidemic effects. Alliin can effectively lower fasting glucose levels, enhance insulin sensitivity, and improve lipid profiles. This suggests a promising potential for its use in preventing and managing metabolic disorders. Additionally, it shows hepatoprotective effects by reducing markers of liver damage and has been linked epidemiologically to a reduced risk of certain cancers, particularly those of the stomach and colon, though more direct research on pure Alliin's anti-cancer mechanisms is ongoing.


For industries seeking high-quality raw materials, NINGBO INNO PHARMCHEM CO.,LTD. stands as a leading manufacturer and reliable supplier of (S)-3-(Allylsulphinyl)-L-alanine (CAS: 556-27-4). Our commitment to stringent quality control ensures that our product meets the highest standards for purity and consistency, making it ideal for pharmaceutical, nutraceutical, and research applications. We offer competitive price structures and provide flexible options for clients looking to buy or purchase this essential compound in bulk. Our robust supply chain ensures efficient delivery to meet your production needs.


While generally considered safe for consumption, especially when sourced responsibly, it is important to acknowledge that some individuals may experience mild side effects such as breath or body odor, or gastrointestinal upset, particularly with high dosages of raw garlic or supplements. Precautions are advised for those on anticoagulant medications due to its anti-clotting properties. With its multifaceted health benefits and growing scientific recognition, (S)-3-(Allylsulphinyl)-L-alanine (Alliin) continues to be a compound of significant interest, offering a wide range of potential applications in health and wellness products globally.

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