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What is 1-Fluoro-10-iododecane? Applications in Organic Synthesis

In the expansive field of organic chemistry, specialized intermediates are the cornerstone of innovation, enabling the creation of complex molecules for diverse applications. 1-Fluoro-10-iododecane is one such compound, offering unique structural features that make it a valuable tool for synthetic chemists. As a leading manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. is pleased to provide detailed information on this important chemical.

Chemical Identity and Properties
1-Fluoro-10-iododecane, with the CAS number 512783-29-8, is a halogenated alkane with the molecular formula C10H20FI. Its structure consists of a ten-carbon chain with a fluorine atom at one end and an iodine atom at the other. This difunctionalization is key to its utility. Physically, it is a colorless transparent liquid with a density of approximately 1.3 g/mL. Its relatively high boiling point (around 283.7°C) and refractive index (1.477) are important parameters for its handling and use in synthetic reactions. The chemical itself is typically supplied with a high assay of ≥99.0%, ensuring high purity for critical applications, and a moisture content of ≤0.05% for stability.

Key Applications in Organic Synthesis
The primary value of 1-Fluoro-10-iododecane lies in its role as an organic synthesis intermediate. Its two distinct halogen functionalities allow for sequential or selective reactions:

  • Introduction of Fluorine: Fluorine atoms are highly sought after in drug discovery and materials science due to their ability to enhance lipophilicity, metabolic stability, and binding affinity. Using 1-Fluoro-10-iododecane allows chemists to strategically incorporate a fluorine atom into a molecule.
  • Versatile Iodine Reactivity: The iodine atom is an excellent leaving group for nucleophilic substitutions and is highly reactive in various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Heck). This enables the formation of complex carbon-carbon bonds, crucial for building intricate molecular structures.
  • Building Block for Complex Molecules: Researchers can utilize this compound as a bifunctional linker or as a starting point for synthesizing more complex fluoro-iodo compounds or other difunctionalized alkanes.

Sourcing with Confidence from NINGBO INNO PHARMCHEM CO.,LTD.
When you choose to buy 1-Fluoro-10-iododecane, selecting a reliable supplier is crucial. As a prominent manufacturer in China, we guarantee product quality, competitive prices, and dependable supply. Our efficient production processes and stringent quality control ensure that you receive a product that meets your exact specifications. We offer flexible packaging solutions, including 200 kg drums, and provide global shipping to facilitate your procurement needs. Making a purchase from us means investing in the success of your research.

Conclusion
1-Fluoro-10-iododecane is an indispensable tool for modern organic synthesis. NINGBO INNO PHARMCHEM CO.,LTD. is your trusted partner for high-purity, reliably supplied chemical intermediates. Contact us to learn more about its applications and to secure your supply.

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