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The field of peptide synthesis has seen remarkable growth, driven by the therapeutic potential of peptide-based drugs and the increasing demand for custom peptides. At the heart of efficient peptide synthesis lies the selection of appropriate activated amino acid derivatives. N-Benzyloxycarbonyl-beta-alanine N-hydroxysuccinimide ester, widely known as Z-beta-ALA-OSU (CAS 53733-97-4), is a prime example of such a critical reagent, as emphasized by NINGBO INNO PHARMCHEM CO.,LTD.
Z-beta-ALA-OSU is a specialized amino acid derivative that features an N-hydroxysuccinimide (NHS) ester. This NHS ester serves as a highly effective activating group for the carboxyl terminus of the beta-alanine residue. In peptide synthesis, this activation is crucial for facilitating the formation of a peptide bond with the free amino group of another amino acid or peptide fragment. The reaction proceeds smoothly, often with minimal side product formation, a characteristic that makes the 'buy Z-beta-ALA-OSU' search a common one among peptide chemists.
The N-Benzyloxycarbonyl (Z) protecting group on the alpha-amino position of the beta-alanine is another key feature of Z-beta-ALA-OSU. The Z group is widely used in peptide chemistry due to its stability under various reaction conditions and its facile removal via catalytic hydrogenation or treatment with HBr in acetic acid. This orthogonal deprotection strategy is fundamental to solid-phase peptide synthesis and solution-phase methods alike.
The inherent quality of Z-beta-ALA-OSU, such as the high purity of ≥98.5% and low moisture content of 0.25% supplied by NINGBO INNO PHARMCHEM CO.,LTD., directly impacts the success of peptide elongation. Impurities or excess moisture can lead to side reactions, reduced coupling efficiency, and ultimately, lower yields of the desired peptide sequence. Therefore, sourcing from reputable manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. is paramount for ensuring the quality of 'peptide synthesis reagents'.
Beyond its direct role in peptide chain assembly, Z-beta-ALA-OSU can also be employed in the modification of peptides and proteins, or as a building block in the synthesis of peptidomimetics. Its versatility makes it a valuable asset in the laboratory for researchers aiming to develop novel peptide-based therapeutics or probes for biological studies. The consistent performance of this amino acid derivative solidifies its importance in the ongoing advancements within peptide chemistry.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
