NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supplying high-quality chemicals that drive scientific discovery. Today, we focus on Aztreonam (CAS 78110-38-0), a synthetic antibiotic distinguished by its precise targeting of Gram-negative bacterial pathogens. Its unique chemical structure and mechanism of action make it a cornerstone in research aimed at understanding and combating these challenging microorganisms.

Aztreonam's therapeutic efficacy stems from its ability to interfere with the synthesis of peptidoglycan, a vital component of the bacterial cell wall. Specifically, it binds with high affinity to Penicillin-Binding Protein 3 (PBP3), an enzyme essential for cell division and maintaining the shape of Gram-negative bacteria. This targeted inhibition disrupts the formation of a stable cell wall, leading to bacterial death. This precision in targeting PBP3 is a key aspect that differentiates Aztreonam and makes it a subject of interest for pharmaceutical researchers.

The practical applications of Aztreonam in research are vast. For instance, scientists use it to study the susceptibility of various Gram-negative species, including common culprits of infections like Escherichia coli and Pseudomonas aeruginosa. By analyzing how these bacteria respond to Aztreonam, researchers can identify resistance patterns and develop new strategies to overcome them. The stability of Aztreonam against beta-lactamases is particularly noteworthy, as it allows for studies that explore the evolution and mechanisms of bacterial resistance to widely used antibiotic classes.

When considering the purchase of Aztreonam for laboratory use, the quality and consistency provided by suppliers like NINGBO INNO PHARMCHEM CO.,LTD. are crucial. The price of Aztreonam reflects its sophisticated production and its role in critical research areas. Understanding the buy options and the importance of reliable sourcing is essential for any research institution. The availability of Aztreonam as a pure chemical compound supports advancements in fields ranging from microbiology to drug development.

In essence, Aztreonam’s targeted action against Gram-negative bacteria, coupled with its unique biochemical properties, establishes it as a critical compound in scientific inquiry. Its study continues to illuminate pathways for developing more effective treatments and understanding the intricate dynamics of bacterial infections.