In the ongoing battle against bacterial infections, understanding the nuances of antibiotic action and resistance is paramount. NINGBO INNO PHARMCHEM CO.,LTD. is proud to highlight Aztreonam, a synthetic antibiotic with a distinctive profile that makes it invaluable for scientific research, particularly in the field of antibiotic resistance.

Aztreonam, identified by its CAS number 78110-38-0, belongs to the monobactam class of antibiotics. Unlike traditional beta-lactams, it possesses a single beta-lactam ring, which contributes to its unique stability and spectrum of activity. Its primary mechanism of action is the potent inhibition of bacterial cell wall synthesis. This is achieved by selectively binding to Penicillin-Binding Protein 3 (PBP3), an enzyme critical for the structural integrity of the bacterial cell wall in Gram-negative bacteria. By disrupting this process, Aztreonam effectively leads to bacterial cell lysis and death.

One of the most compelling aspects of Aztreonam for researchers is its inherent stability against many beta-lactamase enzymes. These enzymes are a major reason for antibiotic resistance, as they can chemically inactivate beta-lactam antibiotics. Aztreonam's resistance to these enzymes allows it to remain active against a range of bacteria that have developed resistance to other common antibiotics. This property makes it an excellent tool for studying the mechanisms of beta-lactamase production and evolution in bacteria.

The ability of Aztreonam to specifically target Gram-negative bacteria, including notoriously difficult-to-treat pathogens like Pseudomonas aeruginosa, further enhances its utility. Researchers often employ Aztreonam to investigate the susceptibility patterns of various Gram-negative strains and to understand how bacteria evade or adapt to antibiotic therapies. By examining the interactions of Aztreonam with bacterial targets, scientists gain deeper insights into bacterial physiology and develop strategies to overcome resistance.

The purchase of high-quality Aztreonam from a reliable supplier like NINGBO INNO PHARMCHEM CO.,LTD. ensures that researchers have access to a pure and consistent product for their experiments. The price point of Aztreonam reflects its complex synthesis and critical role in advancing our understanding of infectious diseases. When considering the buy options for research-grade chemicals, the purity and reliability offered by NINGBO INNO PHARMCHEM CO.,LTD. are essential for obtaining meaningful results in the study of antibiotic resistance mechanisms and the inhibition of bacterial cell wall synthesis.

In summary, Aztreonam is more than just an antibiotic; it is a crucial research chemical that aids in dissecting the complexities of bacterial defense. Its specific action, stability against beta-lactamases, and focus on Gram-negative bacteria make it an indispensable tool for scientists working to combat the growing threat of antimicrobial resistance.