Iron is a vital micronutrient, essential for life, playing a crucial role in oxygen transport via hemoglobin and numerous enzymatic functions. Iron deficiency is the most common nutritional deficiency worldwide, leading to iron deficiency anemia (IDA). The management of IDA often involves iron supplementation, and understanding the science behind different iron compounds is key to effective treatment.

Ferrous fumarate, with its CAS number 141-01-5, is a ferric iron salt commonly prescribed for IDA. The 'ferrous' designation indicates that the iron is in the +2 oxidation state, which is more readily absorbed by the intestinal tract than ferric (+3) iron. The fumarate component is an organic acid that pairs with the iron.

The absorption of iron is a complex process influenced by several factors. Ferrous iron is absorbed in the duodenum. Its absorption is enhanced by vitamin C (ascorbic acid), which reduces ferric iron to the more absorbable ferrous form and forms a soluble chelate with it. Conversely, absorption can be inhibited by phytates (found in grains and legumes), polyphenols (found in tea and coffee), and calcium. For this reason, taking iron supplements like ferrous fumarate on an empty stomach, at least an hour before or two hours after meals, is often recommended to maximize absorption, although taking it with food may be necessary to mitigate gastrointestinal side effects.

The typical dosage of ferrous fumarate for adults is often around 65 mg of elemental iron per day, which corresponds to approximately 200 mg of ferrous fumarate. However, the exact dosage should be determined by a healthcare provider based on the severity of anemia and individual needs. It's important to note that while ferrous fumarate is effective, common side effects can include gastrointestinal distress such as constipation, nausea, and diarrhea. These can often be managed by adjusting the dose, taking the supplement with food, or using stool softeners.

The efficacy of ferrous fumarate cas 141-01-5 is well-supported by clinical studies, showing significant improvements in hemoglobin and ferritin levels in patients with IDA. Its role as a cost-effective and widely available iron supplement makes it a cornerstone in the treatment of iron deficiency anemia. If you are considering iron supplementation, consulting a healthcare professional is the best way to ensure you choose the right product and dosage for your specific health needs.