1-Bromo-2,3-difluorobenzene (CAS 38573-88-5): A Key Intermediate for Targeted Drug Development
The pharmaceutical industry constantly seeks novel compounds to develop more effective and targeted drug therapies. Central to this endeavor is the availability of specialized chemical intermediates that can be used to build complex molecular structures. 1-Bromo-2,3-difluorobenzene, with its CAS number 38573-88-5, has emerged as a critical pharmaceutical intermediate, valued for its unique halogenated aromatic structure and its ability to facilitate the synthesis of Active Pharmaceutical Ingredients (APIs).
The incorporation of fluorine atoms into drug molecules is a well-established strategy in medicinal chemistry, often leading to improved metabolic stability, increased lipophilicity, and enhanced binding affinity to target proteins. 1-Bromo-2,3-difluorobenzene, being a difluorinated bromobenzene derivative, provides an excellent scaffold for introducing these desirable fluorine substituents. The bromine atom acts as a reactive handle, allowing for versatile functionalization through various coupling reactions. This makes it an invaluable component in multi-step synthetic routes leading to innovative pharmaceuticals. The compound's purity, typically exceeding 98%, is crucial for ensuring the efficacy and safety of the final drug product, making it a preferred choice for API synthesis.
Ningbo Inno Pharmchem Co., Ltd. is dedicated to supporting the pharmaceutical sector by supplying high-quality 1-Bromo-2,3-difluorobenzene. We understand that reliable access to such intermediates is fundamental for research and manufacturing. Our product adheres to stringent quality standards, ensuring consistency and reproducibility in chemical processes. The demand for this specific brominated difluorobenzene derivative is driven by its successful application in developing advanced therapeutic agents, such as those targeting neurological conditions like migraine. The ability to efficiently synthesize compounds like RIMEGEPANT SULFATE showcases the practical importance of this intermediate.
The chemical properties of 1-Bromo-2,3-difluorobenzene, including its liquid form and specific boiling point and density, contribute to its ease of use in a laboratory setting. However, like many specialized chemicals, it requires careful handling and appropriate storage to maintain its stability and purity. As a key supplier, we provide necessary guidance on these aspects to our clients. The ongoing quest for new treatments necessitates a constant supply of innovative building blocks, and 1-Bromo-2,3-difluorobenzene is undoubtedly one of them. Its role in constructing fluorinated aromatic systems essential for modern drug design cannot be overstated.
In conclusion, 1-Bromo-2,3-difluorobenzene is an indispensable pharmaceutical intermediate that empowers targeted drug development. Its unique chemical structure and reactivity make it a cornerstone in the synthesis of novel APIs. Ningbo Inno Pharmchem Co., Ltd. is committed to providing this vital compound to researchers and manufacturers, facilitating the creation of next-generation medicines that can improve patient outcomes.
Perspectives & Insights
Logic Thinker AI
“However, like many specialized chemicals, it requires careful handling and appropriate storage to maintain its stability and purity.”
Molecule Spark 2025
“The ongoing quest for new treatments necessitates a constant supply of innovative building blocks, and 1-Bromo-2,3-difluorobenzene is undoubtedly one of them.”
Alpha Pioneer 01
“Its role in constructing fluorinated aromatic systems essential for modern drug design cannot be overstated.”