1-Bromo-2,3-difluorobenzene: A Cornerstone in Advanced Chemical Synthesis
Unlock new possibilities in drug discovery with this versatile pharmaceutical intermediate.
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1-Bromo-2,3-difluorobenzene
This compound, identified by CAS 38573-88-5, is a vital halogenated aromatic building block, predominantly used as a pharmaceutical intermediate. Its molecular formula C6H3BrF2 and molecular weight of 192.99 underscore its specific chemical structure, enabling precise reactions in complex organic synthesis pathways.
- As a critical 1-bromo-2,3-difluorobenzene pharmaceutical intermediate, it plays a key role in developing novel drug candidates.
- The unique fluorinated aromatic structure of 2,3-difluorobromobenzene makes it indispensable for medicinal chemistry applications, influencing drug efficacy and pharmacokinetic properties.
- Its utility extends to advanced organic synthesis, where it serves as a versatile building block for creating complex molecules with specific biological activities.
- Leveraging the properties of this chemical intermediate allows for efficient cross-coupling reactions, essential for modern API synthesis.
Key Advantages
Enhanced Reactivity
The presence of both bromine and fluorine atoms on the benzene ring provides orthogonal reactivity, facilitating regioselective functionalization crucial for 1-bromo-2,3-difluorobenzene synthesis strategies.
Improved Bioactivity
Utilizing fluorinated aromatic compounds like this one in medicinal chemistry can lead to drug molecules with enhanced lipophilicity, metabolic stability, and target binding affinity.
Synthetic Versatility
This compound is instrumental in various transition metal-catalyzed reactions, including Suzuki-Miyaura coupling and Buchwald-Hartwig amination, essential for constructing complex pharmaceutical raw materials.
Key Applications
Pharmaceutical Synthesis
As a vital 1-bromo-2,3-difluorobenzene pharmaceutical intermediate, it is employed in the synthesis of Active Pharmaceutical Ingredients (APIs) and drug candidates.
Agrochemical Development
The compound is utilized in the creation of advanced agrochemicals, benefiting from the unique properties conferred by its halogen substituents.
Materials Science
Its unique structure makes it valuable in the development of specialty polymers and materials, leveraging the properties of fluorinated aromatics.
Research and Development
Serves as a key building block in academic and industrial research for exploring new synthetic methodologies and developing novel fluorinated compounds.