Understanding the fundamental properties and synthesis pathways of key chemical compounds is vital for advancing research and development. 2-Phenyl-1,3-propanediol (CAS: 1570-95-2) is a compound that merits close examination due to its diverse roles in organic chemistry, biochemistry, and materials science. With a molecular formula of C9H12O2 and a molecular weight of 152.19 g/mol, this diol offers a unique combination of an aromatic phenyl group and two reactive hydroxyl groups.

The chemical properties of 2-Phenyl-1,3-propanediol are well-documented. It typically appears as a white to off-white solid, with a melting point in the range of 53-56 °C. Its boiling point is approximately 176 °C at 13 Torr. The compound is soluble in solvents like methanol and chloroform, though only slightly. Stability is a key consideration, with the compound being somewhat hygroscopic, requiring appropriate storage conditions. Its chemical structure makes it susceptible to various reactions, including oxidation, reduction, and derivatization, which are foundational to its utility in synthesis.

Several synthesis methods are employed to produce 2-Phenyl-1,3-propanediol. A common route involves the reduction of diethyl phenyl malonate using reducing agents such as lithium aluminum hydride or sodium borohydride. Another approach includes the catalytic hydrogenation of nitro derivatives. Researchers are also exploring biocatalytic pathways for stereoselective synthesis, aiming to produce specific enantiomers for pharmaceutical applications. The efficiency and scalability of these synthesis methods are crucial for making the compound available for commercial use.

The applications of 2-Phenyl-1,3-propanediol are extensive and continue to expand. In pharmaceutical research, it is a critical intermediate for synthesizing anticonvulsant drugs and other APIs. Its role as a substrate for eukaryotic lipase enzymes opens avenues in biochemical studies and biocatalysis. Furthermore, in polymer chemistry, it serves as a monomer for creating advanced polymers with enhanced thermal and mechanical properties. Its use in cosmetic formulations as a humectant also contributes to its market demand.

For chemical researchers and formulators, access to high-purity 2-phenyl-1,3-propanediol is often a prerequisite for successful experimental outcomes. This highlights the importance of reliable sourcing from chemical intermediate manufacturers who adhere to strict quality control. Whether for small-scale laboratory work or larger production runs, understanding the specifications and supply chain of this versatile chemical is key.

In conclusion, 2-Phenyl-1,3-propanediol is a compound of significant importance in modern chemical research and industry. Its distinct properties, coupled with established and emerging synthesis methods, make it an indispensable intermediate for pharmaceutical development, polymer science, and beyond. Ensuring access to this compound through reputable suppliers is fundamental for those engaged in cutting-edge chemical synthesis and product innovation.