Boc-2-bromo-L-phenylalanine: A Versatile Intermediate in Chemical Synthesis
NINGBO INNO PHARMCHEM CO.,LTD. specializes in providing high-quality chemical intermediates that empower innovation across diverse scientific disciplines. Among our comprehensive offerings, Boc-2-bromo-L-phenylalanine (CAS 261165-02-0) stands out as a particularly versatile compound, crucial for advanced chemical synthesis, particularly in peptide chemistry and drug development.
The utility of Boc-2-bromo-L-phenylalanine stems from its carefully designed molecular structure. As a derivative of the naturally occurring amino acid L-phenylalanine, it retains the chiral center and the basic amino acid framework. The key modifications are the N-terminal tert-butyloxycarbonyl (BOC) protecting group and the bromine atom substituted at the 2-position of the phenyl ring. The BOC group is an essential tool in peptide synthesis, offering protection to the amino group during coupling reactions. This protection is readily removable under acidic conditions, allowing for controlled chain elongation, a fundamental process in creating peptides with precise sequences. Researchers frequently look to buy Boc-2-bromo-L-phenylalanine to ensure efficient and selective peptide assembly.
The bromine atom on the phenyl ring provides a reactive handle that significantly expands the synthetic possibilities. Brominated aromatic compounds are cornerstone intermediates in modern organic synthesis, particularly in palladium-catalyzed cross-coupling reactions. These reactions, such as the Suzuki, Heck, and Sonogashira couplings, allow for the precise introduction of new carbon-carbon or carbon-heteroatom bonds. This capability is invaluable for constructing complex molecular architectures found in pharmaceuticals, agrochemicals, and advanced materials. For instance, incorporating specific aromatic substituents via coupling reactions can dramatically alter a molecule's biological activity or physical properties.
The chemical properties of Boc-2-bromo-L-phenylalanine, including its typical appearance as a white crystalline powder and its solubility in common organic solvents, make it convenient to handle and use in laboratory settings. The price point for this specialized reagent is reflective of its intricate synthesis and the high purity standards required for its applications. NINGBO INNO PHARMCHEM CO.,LTD. ensures that researchers can procure this vital intermediate with confidence, knowing that quality and consistency are maintained.
In summary, Boc-2-bromo-L-phenylalanine is more than just an amino acid derivative; it is a gateway to synthesizing complex and functional molecules. Its dual protection and reactive functionalities make it an indispensable intermediate for chemists pushing the boundaries of scientific discovery. NINGBO INNO PHARMCHEM CO.,LTD. is committed to supplying this critical component, facilitating progress in chemical synthesis and beyond.
Perspectives & Insights
Alpha Spark Labs
“specializes in providing high-quality chemical intermediates that empower innovation across diverse scientific disciplines.”
Future Pioneer 88
“Among our comprehensive offerings, Boc-2-bromo-L-phenylalanine (CAS 261165-02-0) stands out as a particularly versatile compound, crucial for advanced chemical synthesis, particularly in peptide chemistry and drug development.”
Core Explorer Pro
“The utility of Boc-2-bromo-L-phenylalanine stems from its carefully designed molecular structure.”