The development and availability of effective treatments for cardiovascular diseases are paramount to global public health. At the heart of many such treatments, like the Sartan-class drugs, lies a critical chemical intermediate: 4-Bromomethyl-2-cyanobiphenyl, known by its CAS number 114772-54-2.

This compound, typically presenting as an off-white crystalline powder, is characterized by its high purity, often exceeding 99.0%. Its molecular formula, C14H10BrN, and a molecular weight of around 272.14 g/mol, point to a complex structure essential for its role in synthesizing active pharmaceutical ingredients (APIs). Key physical properties, such as a melting point of 125-128°C, and its limited solubility in water, are critical for its industrial handling and integration into manufacturing processes.

The paramount application of 4-Bromomethyl-2-cyanobiphenyl is its function as a key intermediate in the pharmaceutical synthesis of Sartan drugs. Medications like Losartan and Olmesartan, which are Angiotensin II Receptor Blockers (ARBs), are widely prescribed to manage hypertension and heart failure. The precisely placed functional groups on the 4-Bromomethyl-2-cyanobiphenyl molecule facilitate the complex chemical reactions required to produce these vital APIs, thereby directly contributing to improved cardiovascular health outcomes for millions worldwide.

Its significance extends to its role in ensuring the quality and safety of these medications. Research involving this intermediate helps in identifying and quantifying potential impurities, a critical aspect of drug development and regulatory compliance. This makes it not just a building block, but also a tool for quality assurance in the pharmaceutical industry. The consistent demand for Sartan drugs means that a reliable and uninterrupted supply of 4-Bromomethyl-2-cyanobiphenyl is essential for global healthcare.

For pharmaceutical companies seeking to procure this vital intermediate, China offers a robust supply chain. Chinese manufacturers are at the forefront of producing high-purity API intermediates, leveraging advanced technologies and stringent quality control measures. Sourcing 4-Bromomethyl-2-cyanobiphenyl from a reputable manufacturer in China provides access to competitive pricing, scalable production, and consistent quality, all of which are critical for maintaining manufacturing efficiency and meeting the ever-growing global demand for effective cardiovascular treatments. Ensuring a stable supply of this crucial intermediate is a key step in supporting global health initiatives.