Understanding the detailed chemical profile of intermediates is fundamental for effective synthesis and research. NINGBO INNO PHARMCHEM CO.,LTD. provides an in-depth look at 2-chloro-3-fluoroaniline (CAS 21397-08-0), a compound essential for various chemical applications, particularly in the pharmaceutical and fine chemical sectors.

2-Chloro-3-fluoroaniline, identified by its CAS number 21397-08-0, has the molecular formula C6H5ClFN and a molecular weight of 145.56. This chemical structure features an aniline ring substituted with a chlorine atom at the ortho position and a fluorine atom at the meta position relative to the amino group. This unique arrangement of halogens and the amine functional group contributes to its distinct chemical reactivity and utility.

The physical properties of 2-chloro-3-fluoroaniline include a reported boiling point in the range of 210-215 °C and a density of approximately 1.349 g/cm³. While some sources describe it as a powder, others indicate it can exist as a liquid. These properties are important considerations for handling, storage, and reaction design. The synthesis of 2-chloro-3-fluoroaniline typically involves the reduction of the corresponding nitro compound, a process that NINGBO INNO PHARMCHEM CO.,LTD. meticulously manages to ensure high purity and consistent quality for its clients.

The primary applications of 2-chloro-3-fluoroaniline lie in its role as an intermediate in organic synthesis. It is frequently used in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. The fluorine atom, in particular, can impart desirable properties to drug molecules, such as increased metabolic stability and enhanced lipophilicity, which can improve drug efficacy and bioavailability. Its utility extends to the creation of various heterocyclic compounds and other complex organic structures.

NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supplying researchers and manufacturers with high-quality chemical intermediates. Our expertise in handling and synthesizing compounds like 2-chloro-3-fluoroaniline ensures that our customers receive products that meet stringent quality standards. By understanding the chemical profile and applications of such compounds, we empower scientific innovation and contribute to the development of new chemical products and processes.