Posted by NINGBO INNO PHARMCHEM CO.,LTD.

Antipyrine, also known as Phenazone, is a synthetic organic compound with the molecular formula C11H12N2O. Its chemical structure, featuring a pyrazolone ring system, is central to its pharmacological activity. Identified by the CAS number 60-80-0, this substance is a cornerstone in the field of pharmaceutical chemistry, serving as a vital intermediate and an active ingredient in various medications.

The synthesis of Antipyrine typically involves the condensation of phenylhydrazine with ethyl acetoacetate, followed by methylation. This process results in a white crystalline powder, which is the common form in which Antipyrine is supplied. Its physical properties, such as a melting point of around 109-111°C, are well-documented and crucial for quality control during manufacturing. The consistent production of high-purity Antipyrine powder is a testament to the advancements in chemical synthesis and processing.

The primary applications of Antipyrine stem from its potent analgesic and antipyretic effects. It has been historically used to alleviate pain and reduce fever. In modern pharmaceutical contexts, it continues to be valued as a pharmaceutical raw material. Furthermore, its utility extends to scientific research, particularly in pharmacology, where it is employed in Antipyrine for drug metabolism studies. This application leverages its known interactions with liver enzymes to understand how the body processes various drugs.

The global availability of Antipyrine as a phenylone intermediate supply is supported by numerous manufacturers worldwide. Companies specializing in fine chemicals and pharmaceutical intermediates ensure a steady supply of this compound, meeting various purity requirements, often exceeding 98%. This ensures that researchers and pharmaceutical developers have access to reliable materials for their critical work, whether it's developing new analgesic drugs or conducting complex biochemical research.

Understanding the chemical profile of Antipyrine is essential for anyone involved in its procurement or use. From its synthesis to its diverse applications, the compound remains a significant player in the pharmaceutical and chemical industries. The consistent demand for this high-quality intermediate highlights its enduring value and importance in advancing healthcare and scientific understanding.