The piperidine ring is a ubiquitous and highly valuable structural motif in medicinal chemistry, appearing in a vast number of pharmaceutical compounds. Its presence often imparts favorable pharmacological and pharmacokinetic properties, making piperidine derivatives highly sought-after building blocks in drug research and development. Ethyl cis-4-amino-3-methoxypiperidine-1-carboxylate monohydrochloride is a notable example of such a versatile intermediate, playing a crucial role in the construction of complex drug molecules.

The significance of this specific piperidine derivative lies not only in its structural features but also in its high purity (≥98%), which is indispensable for pharmaceutical applications. Its use as an intermediate, particularly in the synthesis of Cisapride, highlights its contribution to the development of gastrointestinal motility agents. The precise stereochemistry of the compound, indicated by 'cis' and the specific chiral centers, is often critical for the biological activity of the final drug. This demands rigorous control during synthesis and purification.

Researchers in drug discovery often utilize such building blocks to create libraries of compounds for screening against various biological targets. The availability of readily synthesized and characterized intermediates like Ethyl cis-4-amino-3-methoxypiperidine-1-carboxylate streamlines this process, allowing for faster exploration of structure-activity relationships (SAR). The chemical data, including its CAS number (83863-71-2), molecular formula (C9H19ClN2O3), and molecular weight (238.71200), are essential for accurate documentation and collaboration within research teams.

Furthermore, the handling and storage of these materials are governed by strict protocols to maintain their chemical integrity. Keeping them in cool, dry, and well-closed containers, away from adverse environmental conditions, is standard practice. This ensures that when these building blocks are employed in synthesis, they contribute positively to the desired molecular architecture without introducing unwanted side reactions or impurities. The continued advancement in synthetic organic chemistry provides access to an ever-growing array of such sophisticated building blocks, fueling innovation in pharmaceutical R&D.