The Crucial Role of tert-butyl (R)-(1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate in Modern Pharmaceuticals
In the dynamic world of pharmaceutical manufacturing, the quality and availability of intermediate compounds are paramount. One such critical intermediate that has garnered significant attention is tert-butyl (R)-(1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate, identified by its CAS number 1426129-50-1. This compound serves as a linchpin in the synthesis of essential cardiovascular medications, most notably Sacubitril, a component of the widely prescribed heart failure treatment, Sacubitril/valsartan.
The chemical structure of tert-butyl (R)-(1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate, with its biphenyl moiety and protected amine group, provides the necessary foundation for building complex active pharmaceutical ingredients (APIs). Its high purity, typically exceeding 99%, is a non-negotiable requirement for pharmaceutical applications, ensuring that the final drug product is both safe and effective. The meticulous control over its synthesis and purification reflects the stringent demands of the pharmaceutical industry.
Understanding the applications of this intermediate extends beyond its primary use in Sacubitril production. As a chiral building block, it offers significant potential in various organic synthesis pathways. Researchers and manufacturers seeking to develop new therapies or optimize existing production processes often look for reliable suppliers of such advanced chemical intermediates. The consistent availability and quality of these compounds directly impact research timelines and production efficiency.
For pharmaceutical companies and research institutions, securing a dependable supply chain for critical intermediates like tert-butyl (R)-(1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate is a strategic imperative. Factors such as batch-to-batch consistency, adherence to pharmacopeial standards, and efficient logistics play a crucial role in supplier selection. The ability to purchase this intermediate at a competitive price without compromising on quality is essential for managing manufacturing costs.
NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-quality pharmaceutical intermediates to support the global healthcare industry. Our commitment to excellence ensures that we meet the rigorous standards required for pharmaceutical synthesis, empowering our clients to bring life-changing medications to market. Whether you are involved in large-scale manufacturing or cutting-edge research, partnering with a trusted supplier for your chemical needs is key to success.
Perspectives & Insights
Molecule Vision 7
“Factors such as batch-to-batch consistency, adherence to pharmacopeial standards, and efficient logistics play a crucial role in supplier selection.”
Alpha Origin 24
“The ability to purchase this intermediate at a competitive price without compromising on quality is essential for managing manufacturing costs.”
Future Analyst X
“is dedicated to providing high-quality pharmaceutical intermediates to support the global healthcare industry.”