At NINGBO INNO PHARMCHEM CO.,LTD., we understand that the efficacy of a pharmaceutical tablet hinges on more than just the active pharmaceutical ingredient (API). The excipients, those seemingly inert components, play a critical role in ensuring the drug is delivered effectively. Among these, Sodium Starch Glycolate (SSG) stands out as a powerhouse superdisintegrant, instrumental in optimizing tablet dissolution. Our expertise in sourcing and utilizing high-quality SSG allows us to develop formulations that meet stringent performance standards.

Sodium Starch Glycolate, identified by its CAS No. 9063-38-1, is a modified starch derivative characterized by its remarkable ability to absorb water rapidly and swell significantly. This property is precisely what makes it an exceptional tablet disintegrant. When a tablet containing SSG comes into contact with gastrointestinal fluids, the SSG particles imbibe water, expand, and exert pressure on the tablet matrix. This internal force effectively breaks down the tablet into smaller fragments, increasing the surface area exposed to the dissolution medium. This accelerated disintegration directly translates to faster drug release and, consequently, improved absorption and bioavailability, particularly for poorly soluble APIs.

One of the key advantages of SSG, which we frequently leverage at NINGBO INNO PHARMCHEM CO.,LTD., is its capacity to enhance tablet hardness without compromising its disintegration capabilities. This dual benefit allows for the production of robust tablets that are easy to handle and package, yet still disintegrate rapidly once ingested. The typical usage concentration for SSG in tablet formulations ranges from 2% to 10%, a parameter we meticulously optimize during our formulation development process to achieve the desired performance profile. Its suitability for both direct compression and wet granulation processes further adds to its versatility, making it a go-to excipient for a wide array of oral solid dosage forms.

The selection of the right superdisintegrant is paramount. Factors such as the specific API, the desired release profile, and manufacturing considerations all play a part. However, the proven efficacy, cost-effectiveness, and widespread availability of Sodium Starch Glycolate make it a highly attractive option. By partnering with trusted suppliers and maintaining rigorous quality control, NINGBO INNO PHARMCHEM CO.,LTD. ensures that the SSG we use consistently delivers superior performance. This commitment allows us to develop tablets that not only meet but exceed patient expectations for rapid relief and therapeutic outcomes. For those seeking to improve tablet dissolution and maximize API efficacy, Sodium Starch Glycolate is an indispensable component, and NINGBO INNO PHARMCHEM CO.,LTD. is adept at harnessing its full potential.