Sodium Starch Glycolate: Enhancing Pharmaceutical Tablet Performance
Unlock superior tablet disintegration and dissolution with this key pharmaceutical excipient.
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Sodium Starch Glycolate
Sodium Starch Glycolate (SSG) is a vital pharmaceutical excipient renowned for its potent superdisintegrant properties. It significantly improves tablet disintegration and dissolution rates, which is crucial for enhancing the bioavailability of active pharmaceutical ingredients (APIs). SSG exhibits strong water absorption and rapid expansion capabilities, leading to effective tablet breakdown even in cold water. Its unique mechanism allows for an increase in tablet hardness and improved formability without negatively impacting disintegration properties. This makes it an ideal choice for a wide range of oral solid dosage forms.
- This superdisintegrant swelling properties contribute to rapid tablet breakdown, a key factor in efficient drug delivery.
- The ability to improve tablet hardness without affecting disintegration makes it a versatile choice for tablet formulations.
- Experience fast expansion in cold water, ensuring prompt tablet disintegration and API release.
- Sodium starch glycolate is a cost-effective tablet manufacturing excipient that enhances overall product performance.
Key Advantages Provided by the Product
Enhanced Disintegration and Dissolution
Leveraging its superdisintegrant capabilities, Sodium Starch Glycolate accelerates the breakdown of tablets, facilitating faster drug release and absorption, thereby improving the bioavailability of poorly soluble drugs.
Improved Tablet Physical Properties
SSG can increase tablet hardness and improve formability, offering better tablet integrity and handling without compromising its critical disintegration function, a key aspect for many pharmaceutical formulations.
Versatile Application in Formulations
Its compatibility with various APIs and suitability for processes like direct compression and wet granulation makes it a flexible choice for developing diverse tablet formulations, from immediate-release to controlled-release.
Key Applications
Tablet Formulations
As a leading pharmaceutical excipient for dissolution, SSG is integral to ensuring that tablets disintegrate rapidly after administration, leading to quicker drug absorption.
Capsule Fillers
In capsule formulations, Sodium Starch Glycolate aids in the efficient release of active ingredients, similar to its role in tablets, ensuring timely therapeutic effects.
Oral Suspensions
It functions as a suspension aid, helping to keep powders evenly dispersed in liquid preparations for internal administration, preventing settling and ensuring accurate dosing.
Granule Formation
SSG supports the creation of granules that possess rapid disintegration characteristics, which is beneficial in processes involving granulation for tablet manufacturing.