The Science of Antioxidants: How DPPH (CAS 1898-66-4) Aids Discovery
The relentless scientific pursuit to understand and combat the damaging effects of free radicals has led to a deeper appreciation of antioxidants. These vital molecules protect our cells from oxidative stress, a process linked to aging and numerous chronic diseases. Central to the study of antioxidants is a remarkably stable free radical known as DPPH, or 2,2-Diphenyl-1-picrylhydrazyl (CAS 1898-66-4). Its unique chemical properties have made it an indispensable tool for researchers worldwide.
DPPH's primary function in scientific research is its role as a DPPH free radical scavenger. The compound exhibits a deep violet color in solution, which is characteristic of its radical form. When DPPH interacts with an antioxidant compound capable of donating a hydrogen atom, it is reduced to a stable, non-radical species. This reduction causes a distinct loss of the violet color, which can be precisely measured using spectrophotometric methods. This colorimetric change is the foundation of the widely used antioxidant assay DPPH, which allows for the quantitative evaluation of a compound's ability to neutralize free radicals. The effectiveness of this assay makes DPPH essential for screening new drug candidates, natural products, and dietary supplements for their antioxidant potential.
The reliability of DPPH extends to its application as a standard for Electron Paramagnetic Resonance (EPR) spectroscopy. Its stable radical nature provides a benchmark signal, aiding in the calibration and validation of EPR instruments used to study free radical processes. This dual functionality underscores the importance of DPPH as a versatile chemical reagent. The various DPPH CAS 1898-66-4 uses highlight its significance across different branches of chemistry and biology.
Furthermore, DPPH serves as a critical tool in understanding the broader principles of free radical chemistry. By monitoring the color changes associated with DPPH's reduction, researchers can gain insights into reaction kinetics and mechanisms involving radical intermediates. This makes it valuable not only for applied research but also for fundamental scientific inquiry. As a consistent hydrogen radical scavenger compound, it offers reproducible results, which are the hallmark of good scientific practice.
NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supplying high-quality DPPH to support the scientific community. Our commitment is to provide researchers with the reliable reagents needed to advance their understanding of antioxidants and their role in health and disease.
Perspectives & Insights
Logic Thinker AI
“When DPPH interacts with an antioxidant compound capable of donating a hydrogen atom, it is reduced to a stable, non-radical species.”
Molecule Spark 2025
“This reduction causes a distinct loss of the violet color, which can be precisely measured using spectrophotometric methods.”
Alpha Pioneer 01
“This colorimetric change is the foundation of the widely used antioxidant assay DPPH, which allows for the quantitative evaluation of a compound's ability to neutralize free radicals.”